Tag: M.W:100-200

87392-05-0, Name is (R)-(+)-2-Tetrahydrofuroic acid, belongs to tetrahydrofurans compound, is a common compound. Safety of (R)-(+)-2-Tetrahydrofuroic acidIn an article, once mentioned the new application about 87392-05-0.

LINKED DIBENZIMIDAZOLE DERIVATIVES

The present invention discloses linked dibenzimidazole derivatives, or pharmaceutically acceptable salts, esters, or prodrugs thereof, which inhibit RNA-containing virus, particularly the hepatitis C virus (HCV). Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Product Details of 2144-40-3. Introducing a new discovery about 2144-40-3, Name is (cis-Tetrahydrofuran-2,5-diyl)dimethanol

Total hydrogenation of bio-derived furans over supported Ru subnanoclusters prepared via amino acid-assisted deposition

Development of a highly efficient and robust catalyst with reduced usage of noble metals is extremely desirable for selective hydrogenations of furan-containing bio-based feedstocks, which represents an attractive and sustainable alternative to petrochemical resources. Herein, we describe a new type of well-dispersed Ru subnanoclusters (ca. 0.50 wt%) supported on commercial P25 TiO2 material obtained from a facile and effective amino acid-assisted deposition-precipitation strategy. The as-synthesized catalyst exhibits superior catalytic activity and selectivity for direct hydrogenation of industrially important furfural as well as a range of structurally diverse bio-based furanic compounds to their corresponding fully hydrogenated derivatives. An average turnover frequency (ATOF) value as high as 367 h-1 at 80 C and 4 MPa H2 is obtained, which is the highest reported value. This catalyst also shows stable furfural total hydrogenation in 5 reaction cycles conducted at 80 C (52 mmol-scale, turnover number up to 12?500). In terms of the kinetic and structural characterizations, the key performances of the ultrasmall Ru clusters are proposed to mainly originate from an enhanced number of unsaturated surface Ru atoms and change in local coordination environment. Our work highlights the importance of the subnanometric size of Ru clusters in the advancement of efficient and affordable approaches towards bio-based chemical production.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Product Details of 2144-40-3, you can also check out more blogs about2144-40-3

Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Synthetic Route of 2144-40-3, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.2144-40-3, Name is (cis-Tetrahydrofuran-2,5-diyl)dimethanol, molecular formula is C6H12O3. In a Article，once mentioned of 2144-40-3

Improving the Thermal Properties of Poly(2,5-furandicarboxylate)s Using Cyclohexylene Moieties: A Comparative Study

The search for new polymers from renewable origin is a sparkling field in polymer chemistry, especially those having promising properties, for example, in terms of their thermal performance. In this vein, in this study, an original renewable 2,5-furandicarboxylic acid-based cycloaliphatic homopolyester, poly(1,4-cyclohexylene 2,5-furandicarboxylate) (PCdF), is synthesized from dimethyl-2,5-furandicarboxylate and 1,4-cyclohexanediol. Poly(1,4-cyclohexanedimethylene 2,5-furandicarboxylate) is also prepared for comparison purposes, since it is the direct renewable substitute of poly(1,4-cyclohexanedimethylene terephthalate) and they are structurally related. The resulting homopolyesters are characterized in detail by using attenuated total reflectance Fourier transform infrared, 1H, 13C and 2D NMR, X-ray and elemental analysis, and thermal properties are assessed by thermogravimetric analysis, differential scanning calorimetry, and dynamic mechanical thermal analysis. PCdF shows to have a semicrystalline character, exhibiting an extremely high glass transition temperature around 175 C. Moreover, this polyester also shows to be a high thermally stable material with a degradation temperature of 380.0 C. (Figure presented.).

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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. category: Tetrahydrofurans. Introducing a new discovery about 52449-98-6, Name is Oxolane-2-carbonyl chloride

QUINOLINE COMPOUND

A compound, which has a melanin-concentrating hormone antagonistic action and useful as an agent for preventing or treating obesity, and which is represented by the formula: wherein Aris a cyclic group optionally having substituent(s) ;Xis a bond or a spacer having a main chain of 1 to 6 atoms;R1 and R2are the same or different and each is a hydrogen atom or a hydrocarbon group optionally having substituent(s), or R1 and R2 may form, together with the adjacent nitrogen atom, a nitrogen-containing heterocycle optionally having substituent(s);Yis a divalent hydrocarbon group optionally having substituent(s) (except CO);R3is a hydrogen atom or a hydrocarbon group optionally having substituent(s); andring A and ring Bmay further have substituents, and when ring B further has a substituent, the substituent may be linked to R1 to form a ring, or a salt thereof, or a prodrug thereof, is provided.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.category: Tetrahydrofurans, you can also check out more blogs about52449-98-6

Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Electric Literature of 66838-42-4, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.66838-42-4, Name is (R)-Tetrahydrofuran-3-carboxylic acid, molecular formula is C5H8O3. In a Patent，once mentioned of 66838-42-4

Novel compounds

The present invention relates to novel retinoid-related orphan receptor gamma (RORgamma) modulators and their use in the treatment of diseases mediated by RORgamma.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 66838-42-4

Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Application of 66838-42-4, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.66838-42-4, Name is (R)-Tetrahydrofuran-3-carboxylic acid, molecular formula is C5H8O3. In a Patent，once mentioned of 66838-42-4

AROMATIC DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS

The present invention provides HIV aspartyl protease inhibitors of the formula; and when the compound of formula I comprises an amino group, pharmaceutically acceptable ammonium salts thereof, wherein n is 3 or 4, wherein R 1 may be, for example, iso-butyl, wherein X and Y, same or different, may be, for example, NH 2 and F, and wherein R 2 and R 3 are as defined herein.

We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 66838-42-4, and how the biochemistry of the body works.Application of 66838-42-4

Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Related Products of 4971-56-6, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 4971-56-6, Furan-2,4(3H,5H)-dione, introducing its new discovery.

A simple synthesis of furo[3?,4?:5,6]pyrido[2,3-d]pyrimidine derivatives through multicomponent reactions in water

A series of furo[3?,4?:5,6]pyrido[2,3-d]pyrimidine and indeno[2?,1?:5,6]pyrido[2,3-d]pyrimidine derivatives were synthesized by three-component reactions involving an aldehyde, 2,6-diaminopyrimidine-4(3H)-one, and either tetronic acid or indane-1,3-dione in water, under microwave irradiation and traditional heating conditions, without use of any catalyst. This protocol has the advantages of higher yields, lower cost, reduced environmental impact, and convenience of procedure. The synthesis of a class of important compounds in aqueous medium has been achieved. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Related Products of 4971-56-6. In my other articles, you can also check out more blogs about 4971-56-6

Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Formula: C5H6O4, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 21461-84-7, Name is (S)-( )-5-Oxo-2-tetrahydrofurancarboxylic Acid, molecular formula is C5H6O4

Synthesis and anti-HIV activity of l-2?,3?-Dideoxy-4?-selenonucleosides (l-4?-Se-ddNs)

Based on the potent anti-HIV activity of l-2?,3?-dideoxycytidine (l-ddC), l-2?,3?-dideoxy-4?-selenonucleosides (l-4?-Se-ddNs) have been synthesized from natural chiral template, l-glutamic acid, using Pummerer-type condensation as a key step. All synthesized compounds were assayed for anti-HIV-1 activity, but none of them did show any significant antiviral activity up to 100 muM, probably due to conformational differences between l-ddC and l-4?-Se-ddC, induced by the bulky selenium atom, which might play an important role in phosphorylation by cellular kinase.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Formula: C5H6O4, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 21461-84-7, in my other articles.

Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. name: 3-Methyldihydrofuran-2(3H)-one, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 1679-47-6, name is 3-Methyldihydrofuran-2(3H)-one. In an article，Which mentioned a new discovery about 1679-47-6

Synthesis of antimalarial G-factors endoperoxides: relevant evidence of the formation of a biradical during the autoxidation step

In the search for new antimalarial endoperoxides related to G-factors series, using a methodology based on autoxidation of a dienol sytem, unexpected cyclic ether alcohols and hydroperoxides were obtained confirming the structure of the previously postulated biradical intermediate implicated in oxygen uptake. Antimalarial activities of PMB-endoperoxides are greatly enhanced when the peroxyhemiketal function is methylated for the G3 endoperoxide.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 1679-47-6, help many people in the next few years.name: 3-Methyldihydrofuran-2(3H)-one

Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Electric Literature of 4971-56-6, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.4971-56-6, Name is Furan-2,4(3H,5H)-dione, molecular formula is C4H4O3. In a article，once mentioned of 4971-56-6

[4+2+1] domino cyclization in water for chemo- and regioselective synthesis of spiro-substituted benzo[b]furo[3,4-e][1,4]diazepine derivatives

New regio- and chemoselective [4+2+1] domino cyclization consisting of the formation of two spiro rings and five sigma bonds has been developed for the synthesis of spiro-substituted benzo[b]furo[3,4-e][1,4]diazepine derivatives. The reaction is a multicomponent domino green process and can be readily performed by reacting inexpensive starting materials of benzene-1,2-diamines, tetronic acid and 2,2-dihydroxy-2H-indene-1,3-dione in aqueous solution under microwave irradiation. The present synthesis shows attractive characteristics, such as the use of water as reaction media, convenient one-pot operation, short reaction periods of 10-18 min and reduced waste production without the use of any strong acids or metal promoters. This synthesis serves as a nice addition to GAP (Group-Assistant-Purification) chemistry in which purification via chromatography and recrystallization can be avoided, and the pure products were obtained simply by washing the crude products with 95% EtOH.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 4971-56-6

Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem