Tag: M.W:100-200

Related Products of 117752-88-2, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 117752-88-2, (R)-3-Amino-g-butyrolactone hydrochloride, introducing its new discovery.

Single Step Conversion of Chiral Carnitine and Derivatives into (S)- and (R)-beta-Substituted-gamma-Butyrolactones

This paper describes an efficient single step transformation of chiral carnitine and carnitine derivatives into stereoisomerically pure (S)- and (R)-beta-substituted-gamma-butyrolactones, obtained by intramolecular nucleophilic displacement. (S)- Or (R)-carnitine and (R)-aminocarnitine inner salts give beta-hydroxy-gamma-butyrolactone and beta-amino-gamma-butyrolactone respectively (82% and 77%) with the same configuration as the starting material. (R)-Acetylaminocarnitine inner salt gives (R)-beta-acetylamino-gamma-butyrolactone (90%), while (R)-acetylcarnitine gives 2(5H)-furanone under the same reaction conditions (77%, via cyclization and subsequent elimination reaction). (R)-N-Benzyloxycarnitineamide gives a mixture of pyrrolidinone (11%) and furanoyl imidate (50%) derivatives. The direct transformation of waste (S)-carnitine into the valuable (S)-beta-hydroxy-gamma-butyrolactone or (after acetylation) into the precious 2(5H)-furanone is of particular interest.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Related Products of 117752-88-2. In my other articles, you can also check out more blogs about 117752-88-2

Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Synthetic Route of 52449-98-6, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 52449-98-6, Name is Oxolane-2-carbonyl chloride, molecular formula is C5H7ClO2. In a Patent，once mentioned of 52449-98-6

Method of Flavoring

A method of providing a desirable vanilla beany flavor in an orally-receivable product, includes adding to a product base at least one of divanillyl succinate or at least one compound according to Formula I or Formula II in which R? is selected from the group consisting of hydrogen, methyl and ?CHO, and R is selected from the group consisting of hydrogen. C1-C10 linear alkyl. C3-C10 branched alkyl, C2-C10 linear alkenyl, C3-C10 branched alkenyl, C1-C10 hydroxyalkyl, C2-C10 carboxyalkyl, and tetrahydrofuranyl.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Synthetic Route of 52449-98-6. In my other articles, you can also check out more blogs about 52449-98-6

Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Synthetic Route of 15833-61-1, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 15833-61-1, Name is (Tetrahydrofuran-3-yl)methanol,introducing its new discovery.

Design and optimisation of orally active TLR7 agonists for the treatment of hepatitis C virus infection

The synthesis and structure-activity relationships of a series of novel interferon inducers are described. Pharmacokinetic studies and efficacy assessment of a series of 8-oxo-3-deazapurine analogues led to the identification of compound 33, a potent and selective agonist of the TLR7 receptor with an excellent in vivo efficacy profile in a mouse model.

We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 15833-61-1, and how the biochemistry of the body works.Synthetic Route of 15833-61-1

Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Computed Properties of C4H6O3, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 7331-52-4, Name is (S)-4-Hydroxydihydrofuran-2(3H)-one, molecular formula is C4H6O3

PROCESS FOR PREPARING OPTICALLY ACTIVE 2- 6-(HYDROXY-METHYL)-1,3-DIOXAN-4-YL]ACETIC ACID DERIVATIVES

The present invention is to provide a production technology by which an optically active 2-[6-(hydroxymethyl)-1,3-dioxan-4-yl]acetic acid derivative, which are of value as pharmaceutical intermediates, can be produced from inexpensive and readily available starting materials without using any extraordinary equipment such as an ultra-low-temperature reactor.The present invention is a production process of an optically active 2-[6-(hydroxymethyl)-1,3-dioxan-4-yl]acetic acid derivative, ???which comprises reacting an enolate, prepared by permitting a base or a 0-valent metal to act on an acetic acid ester derivative with (S)-beta-hydroxy-gamma-butyrolactone at a temperature not lower than -30C to give a dihydroxyoxohexanoic acid derivative,???treating the same with an acylating agent in the presence of a base to produce a dihydroxyoxohexanoic acid monoacyl derivative,???reducing this compound with a microorganism to produce a trihydroxyhexanoic acid monoacyl derivative,???treating this compound with an acetal-forming reagent in the presence of an acid catalyst to produce an acyloxymethyldioxanylacetic acid derivative, and, ???finally, subjecting this compound to solvolysis in the presence of a base.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Computed Properties of C4H6O3, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 7331-52-4, in my other articles.

Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

4344-84-7, Name is 5-Oxotetrahydrofuran-2-carboxylic acid, belongs to tetrahydrofurans compound, is a common compound. SDS of cas: 4344-84-7In an article, once mentioned the new application about 4344-84-7.

Asymmetric one-pot reactions using heterogeneous chemical catalysis: Recent steps towards sustainable processes

The preparation of optically pure fine chemicals is among the most important and challenging tasks met by organic chemists. Recently, significant efforts have been focused on the development of green and sustainable procedures for the synthesis of these high value-added compounds. Asymmetric heterogeneous catalysis has provided efficient solutions to these challenges. The application of heterogeneous chiral catalysts in one-pot processes combines the advantages of use of these materials with time, material, and energy savings associated with cascade or sequential procedures. This review surveys these asymmetric one-pot reactions reported until July 2017, in which a heterogeneous chemical catalyst has been applied either as a single multifunctional catalyst or in combination with a second catalytically active material. These processes include one-pot procedures catalysed by carefully designed solids obtained by the immobilization of chiral metal complexes, by anchoring chiral organocatalysts, or by modifying catalytic surfaces with optically pure compounds, which may also incorporate uncatalyzed and homogeneously catalysed steps. Methods applying achiral heterogeneous catalysts in combination with soluble chiral chemical catalysts or biocatalysts are also presented. Sophisticated, finely tuned materials have been applied in most of these reactions, which have been discussed along with the main requirements necessary to perform these transformations in a one-pot manner.

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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Recommanded Product: (Tetrahydrofuran-3-yl)methanamine, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 165253-31-6, Name is (Tetrahydrofuran-3-yl)methanamine, molecular formula is C5H11NO

A tetrahydrofuran – 3 – methylamine synthetic method (by machine translation)

The invention discloses a tetrahydrofuran – 3 – methylamine synthetic method, solved in the prior art tetrahydrofuran – 3 – methylamine synthesis with a route process is complicated, and the cost is high, the problem of harsh reaction conditions. The present invention includes: (1) in the organic solvent in the I, acrylonitrile and ethylene oxide in the presence of a catalyst A produced by the reaction of 3 – cyano – tetrahydrofuran; (2) 3 – cyano – tetrahydrofuran in the organic solvent after the purification catalyst under the condition B II and reduction to obtain tetrahydrofuran – 3 – methylamine. The invention greatly shortens the technological process and production cycle, and is simple, environmental protection, low cost, simple operation, high yield, has significant social and economic benefits and commercial application value. (by machine translation)

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Recommanded Product: (Tetrahydrofuran-3-yl)methanamine, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 165253-31-6, in my other articles.

Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. SDS of cas: 89898-51-1. Introducing a new discovery about 89898-51-1, Name is Ethyl 4-oxotetrahydrofuran-3-carboxylate

Chiral Primary Amine Catalyzed Asymmetric alpha-Benzylation with In Situ Generated ortho-Quinone Methides

A dual activation strategy integrating primary amine catalysis and Lewis base activation has been developed for an asymmetric alpha-benzylation reaction. Enamines derived from beta-ketocarbonyls could react effectively with in situ generated ortho-quinone methides under Lewis base activation in asymmetric alpha-benzylation of beta-ketocarbonyls and alpha-branched aldehydes. The approach enables the creation of acyclic all-carbon quaternary stereocenters with excellent enantioselectivities and good activity.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.SDS of cas: 89898-51-1, you can also check out more blogs about89898-51-1

Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Reference of 4971-56-6, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 4971-56-6, Furan-2,4(3H,5H)-dione, introducing its new discovery.

Unexpected and green synthesis of azapodophyllotoxin derivatives via microwave-assisted multicomponent reactions in ammonia water

An unexpected and green synthesis of azapodophyllotoxin derivatives was realized via microwave-assisted multicomponent reactions of dimedone, tetronic acid, and aromatic aldehydes in ammonia water. This protocol has the advantages of environmental friendliness, short reaction time, good yields, low cost, and easy operation.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Reference of 4971-56-6. In my other articles, you can also check out more blogs about 4971-56-6

Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Recommanded Product: Ethyl tetrahydrofuran-2-carboxylate, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 16874-34-3, Name is Ethyl tetrahydrofuran-2-carboxylate, molecular formula is C7H12O3

Grignard reagent/borohydride combinations alkylation/reduction of esters

The one step transformation of esters into secondary alcohols (70-80% yields) has been performed with a Grignard reagent in the presence of calcium or zinc borohydride. Under the same conditions, vinylic Grignard reagents gave gamma,delta-unsaturated alcohols in good yields through three successive reactions: addition to the ester carbonyl, then conjugate addition and, finally reduction).

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Recommanded Product: Ethyl tetrahydrofuran-2-carboxylate, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 16874-34-3

Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Application of 52079-23-9, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 52079-23-9, Name is (S)-(-)-alpha-Hydroxy-gamma-butyrolactone, molecular formula is C4H6O3. In a Patent，once mentioned of 52079-23-9

LACTAMS AS INHIBITORS OF ROCK

The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application of 52079-23-9. In my other articles, you can also check out more blogs about 52079-23-9

Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem