The Absolute Best Science Experiment for (S)-( )-5-Oxo-2-tetrahydrofurancarboxylic Acid

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Organic chelating ligands, organic chelating ligand precursors, and metal chelates are disclosed. Methods for synthesizing the same are also described, including methods for preparing optically-enriched or optically-pure compositions of the same.

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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Brief introduction of 4971-56-6

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The present invention relates to novel heterocyclic compounds and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. In particular embodiments, the structure of the compounds is given by Formula (I): [image] wherein Q1, Q2, R2, R3, R4, R5, and R6 are as described herein.The invention also relates to methods for the preparation of the compounds, and to pharmaceutical compositions containing such compounds.

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Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

More research is needed about 2,2,5,5-Tetramethyldihydrofuran-3(2H)-one

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Synthetic Route of 5455-94-7, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 5455-94-7, 2,2,5,5-Tetramethyldihydrofuran-3(2H)-one, introducing its new discovery.

When 2,2,5,5-tetramethyltetrahydrofuran-3-one 1 was oxidized with selenium dioxide in ethanol, the title heterocycle 4 was formed along with 2,2,5,5-tetramethyltetrahydro-3,4-furandione 2.The diselenide 4 represents a novel six-membered heterocycle in the chalcogen series.

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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Simple exploration of 637-64-9

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alpha-Cellulose was pyrolyzed using a multimode microwave oven, different microwave absorbers and experimental set ups. The microwave absorber showed a strong influence: carbon gave a large gasification of cellulose (yield of gas up to 53.8%) while Al2O3 gave a high yield of bio-char (64.1%) and a low gas production (3.0%). Bio-oil was obtained with the highest yield (37.6%) using iron as microwave absorber and a condenser between the oven and the collecting system. Dark brown bio-oils having low density and viscosity due to the presence of large amount of furanosidic compounds were collected. Bio-oils were characterized through GC-MS, FT-IR, NMR, The GC-MS analysis was employed to evaluate the composition of bio-oils using calculated retention factors. A high concentration of levoglucosan (133.9 mg/mL) together with acetic acid, acetic anhydride, 1-hydroxy-2-propanone, formic acid and furfural were obtained using graphite as microwave absorber. A mechanisms was proposed to rationalize the formation of aromatic compounds present in bio-oils. Water contents in bio-oils were affected by all parameters of the process, mainly by the microwave absorber. The use of silica has proved to be a promising way to obtain bio-oil with low water content (13%), while pyrolysis in the presence of carbon gave a large amount of water (46%).

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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Awesome Chemistry Experiments For 1679-47-6

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An electrophilic trifluoromethylation of ketene silyl acetals (KSAs) by hypervalent iodine reagents 1 and 2 has been developed. The reaction proceeds under very mild conditions in the presence of a catalytic amount of trimethylsilyl bis(trifluoromethanesulfonyl)imide (up to 2.5 mol %) as a Lewis acid providing a direct access to a variety of secondary, tertiary, and quaternary alpha-trifluoromethyl esters and lactones in high yield (up to 98%).

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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

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The sustainable production of polymers from biogenic platform chemicals shows great promise to reduce the chemical industry’s dependence on fossil resources. In this context, we propose a new two-step process leading from dicarboxylic acids, such as succinic and itaconic acid, to N-vinyl-2-pyrrolidone monomers. Firstly, the biogenic acid is reacted with ethanolamine and hydrogen using small amounts of water as solvent together with solid catalysts. For effective conversion, the optimal catalyst (carbon supported ruthenium) has to hold the ability of activating H2 as well as (imide) CO bonds. The obtained products, N-(2-hydroxyethyl)-2-pyrrolidones, are subsequently converted in a continuous gas phase dehydration over simple sodium-doped silica, with excellent selectivity of above 96 mol% and water as the sole by-product. With a final product yield of ?72 mol% over two process steps and very little waste due to the use of heterogeneous catalysis, the proposed route appears promising-commercially as well as in terms of Green Chemistry.

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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Properties and Exciting Facts About Tetrahydrofuran-3-carboxylic acid

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The heterospirocyclic N-methyl-N-phenyl-5-oxa-1-azaspiro[2.4]hept-1-e n-2-amine (6) and N-(5-oxa-1-azaspiro[2.4]hept-1-en-2-yl)-(S)-proline methyl ester (7) were synthesized from the corresponding heterocyclic thiocarboxamides 12 and 10, respectively, by consecutive treatment with COCl2, 1,4-diazabicyclo[2.2.2]octane, and NaN3 (Schemes 1 and 2). The reaction of these 2H-azirin-3-amines with thiobenzoic and benzoic acid gave the racemic benzamides 13 and 14, and the diastereoisomeric mixtures of the N-benzoyl dipeptides 15 and 16, respectively (Scheme 3). The latter were separated chromatographically. The configurations and solid-state conformations of all six henzamides were determined by X-ray crystallography. With the aim of examining the use of the new synthons in peptide synthesis the reactions of 7 with Z-Leu-Aib-OH to yield a tetrapeptide 17 (Scheme 4), and of 6 with Z-Ala-OH to give a dipeptide 18 (Scheme 5) were performed. The resulting diastereoisomers were separated by means of MPLC or HPLC. NMR Studies of the solvent dependence of the chemical shifts of the NH resonances indicate the presence of an intramolecular H-bond in 17. The dipeptides (S,R)-18 and (S,S)-18 were deprotected at the N-terminus and were converted to the crystalline derivatives (S,R)-19 and (S,S)-19, respectively, by reaction with 4-bromobenzoyl chloride (Scheme 5). Selective hydrolysis of (SR)-18 and (S.S)-18 gave the dipeptide acids (R,S)-20 and (SS)-20, respectively. Coupling of a diastereoisomeric mixture of 20 with H-Phe-O?Bu led to the tripeptides 21 (Scheme 5). X-Ray crystal-structure determinations of (S,R)-19 and (S,S)-19 allowed the determination of the absolute configurations of all diastereoisomers isolated in this series.

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Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

More research is needed about 4971-56-6

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Electric Literature of 4971-56-6, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.4971-56-6, Name is Furan-2,4(3H,5H)-dione, molecular formula is C4H4O3. In a Article,once mentioned of 4971-56-6

Under mild thermal conditions, a [3+3] cycloaddition reaction between an active methylene compound and a dipolar trimethylenemethane species, which is thermally generated from 2-methylenecyclopropanone acetal, provides a dihydropyran.

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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

More research is needed about 2144-40-3

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Polymers are used in simple consumer items like carpets, furniture, glues, and clothing but are also used in advanced engineering, including materials used in the aerospace industry. Therefore, polymers and consequently their monomers play an important role in our everyday life. Currently, most of the monomers are produced from fossil resources, the supply of which is diminishing. In this paper we review strategies and catalytic processes to obtain currently used and potentially new monomers from renewable bio-based feedstocks and platform chemicals. This Review is divided by type of monomer and includes diacids and esters, diols, hydroxy acids and esters, lactones, carbonates, cyclic ethers, diamines, amino acids and lactams, alkenes, acrylics, and conjugated dienes. Only routes based on the use of homogeneous catalysis, heterogeneous catalysis, or bio-catalysis are described. Fermentative processes are not discussed.

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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Discovery of Furan-2,4(3H,5H)-dione

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TiO2 catalyzed reactions between various activated CH-acids and tetracyanoethylene are described. This reaction affords the corresponding pyran annulated heterocyclic systems in high yields at room temperature in 3 h. The work-up procedure is very simple, and the products do not require further purification. The catalysts can be recycled and reused several times without observable loss of performance. Graphical abstract: [Figure not available: see fulltext.]

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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem