Tag: M.W=100-150

Hua, Geng published the artcileOne-pot inimer promoted ROCP synthesis of branched copolyesters using α-hydroxy-γ-butyrolactone as the branching reagent, Recommanded Product: 3-Hydroxydihydrofuran-2(3H)-one, the publication is Journal of Polymer Science, Part A: Polymer Chemistry (2016), 54(13), 1908-1918, database is CAplus and MEDLINE.

An array of branched poly(ε-caprolactone)s was successfully synthesized using an one-pot inimer promoted ring-opening multibranching copolymerization (ROCP) reaction. The biorenewable, com. available yet unexploited comonomer and initiator 2-hydroxy-γ-butyrolactone was chosen as the inimer to extend the use of 5-membered lactones to branched structures and simultaneously avoiding the typical tedious work involved in the inimer preparation Reactions were carried out both in bulk and in solution using stannous octoate (Sn(Oct)₂) as the catalyst. Polymerizations with inimer equivalent varying from 0.01 to 0.2 were conducted which resulted in polymers with a degree of branching ranging from 0.049 to 0.124. Detailed ROCP kinetics of different inimer systems were compared to illustrate the branch formation mechanism. The resulting polymer structures were confirmed by ¹H, ¹³C, and ₁H-₁₃C HSQC NMR and SEC (RI detector and triple detectors). The thermal properties of polymers with different degree of branching were investigated by DSC, confirming the branch formation. Through this work, we have extended the current use of the non-homopolymerizable γ-butyrolactone to the branched polymers and thoroughly examined its behaviors in ROCP. © 2016 Wiley Periodicals, Inc.J. Polym. Sci., Part A: Polym.Chem. 2016.

Journal of Polymer Science, Part A: Polymer Chemistry published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Recommanded Product: 3-Hydroxydihydrofuran-2(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Sander, Kerstin published the artcileDevelopment of Fluorine-18 Labeled Metabolically Activated Tracers for Imaging of Drug Efflux Transporters with Positron Emission Tomography, Recommanded Product: 3-Hydroxydihydrofuran-2(3H)-one, the publication is Journal of Medicinal Chemistry (2015), 58(15), 6058-6080, database is CAplus and MEDLINE.

Increased activity of efflux transporters, e.g., P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP), at the blood-brain barrier is a pathol. hallmark of many neurol. diseases, and the resulting multiple drug resistance represents a major clin. challenge. Noninvasive imaging of transporter activity can help to clarify the underlying mechanisms of drug resistance and facilitate diagnosis, patient stratification, and treatment monitoring. We have developed a metabolically activated radiotracer for functional imaging of P-gp/BCRP activity with positron emission tomog. (PET). In preclin. studies, the tracer showed excellent initial brain uptake and clean conversion to the desired metabolite, although at a sluggish rate. Blocking with P-gp/BCRP modulators led to increased levels of brain radioactivity; however, dynamic PET did not show differential clearance rates between treatment and control groups. Our results provide proof-of-concept for development of prodrug tracers for imaging of P-gp/BCRP function in vivo but also highlight some challenges associated with this strategy.

Journal of Medicinal Chemistry published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Recommanded Product: 3-Hydroxydihydrofuran-2(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Liu, Yuping published the artcileSynthesis and odor evaluation of five new sulfur-containing ester flavor compounds from 4-ethyloctanoic acid, Category: tetrahydrofurans, the publication is Molecules (2010), 5104-5111, database is CAplus and MEDLINE.

Five sulfur-containing flavor compounds were designed. and the synthesis of the target compounds was achieved using 4-ethyloctanoyl chloride and thiols and alcs. as starting materials. The products thus obtained [i.e., 4-ethyloctanoic acid 3-(methylthio)propyl ester, 4-ethyloctanethioic acid S-(2-furanylmethyl) ester, 4-ethyloctanethioic acid S-(2-methyl-3-furanyl) ester, 4-ethyloctanoic acid 2-(4-methyl-5-thiazolyl)ethyl ester, 4-ethyloctanethioic acid S-(tetrahydro-2-methyl-3-furanyl) ester] are synthetic sulfur-containing ester flavor compounds which all possess a meaty odor and might be used in foods if approved for this purpose.

Molecules published new progress about 57124-87-5. 57124-87-5 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Thiol, name is 2-Methyl-3-tetrahydrofuranthiol, and the molecular formula is C5H10OS, Category: tetrahydrofurans.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Liang, Jiajin published the artcileComprehensive insights into xylan structure evolution via multi-perspective analysis during slow pyrolysis process, Synthetic Route of 19444-84-9, the publication is Fuel Processing Technology (2019), 1-7, database is CAplus.

Comprehension in hemicellulose pyrolysis is critical to generate renewable fuel and valuable chem. Herein, a self-designed tubular reactor was applied to observe the appearance alteration and chem. structure evolution during the whole xylan pyrolysis process. Before 200°C, it was free moisture removal stage without significant chem. structure alteration. Xylan began to depolymerize at 200°C corresponding with the appearance change from its original state to dark brown, cleavage of branched-chain and primary product acids & ketones generation. The main chain of xylan was completely broken at 250-350°C via β-1,4-glycosidic bond cleavage, dehydration, decarboxylation, and decarbonylation reaction. Acids were mainly originated from hemicellulose pyrolysis. The typical signals from FTIR, ¹³C CP/MAS NMR were disappeared at 350°C. In the carbonation stage, the C/H and C/O ratio reached 2.01 and 4.54, leading to the aromaticity enhancement of char and formation of carbon-centered radicals.

Fuel Processing Technology published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Synthetic Route of 19444-84-9.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Xie, Long-Yong published the artcileVisible-light-promoted direct C-H/S-H cross-coupling of quinoxalin-2(1H)-ones with thiols leading to 3-sulfenylated quinoxalin-2(1H)-ones in air, Category: tetrahydrofurans, the publication is Organic Chemistry Frontiers (2019), 6(24), 3950-3955, database is CAplus.

A new and efficient visible-light-mediated strategy was developed for the synthesis of 3-sulfenylated quinoxalin-2(1H)-ones via direct C-H sulfenylation of quinoxalin-2(1H)-ones with thiols in air at room temperature Through this photochem. reaction, various 3-sulfenylated quinoxalin-2(1H)-ones were be efficiently and conveniently obtained in excellent yields with good functional group tolerance by simple use of rhodamine B as the cheap photocatalyst and air as the green oxidant.

Organic Chemistry Frontiers published new progress about 57124-87-5. 57124-87-5 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Thiol, name is 2-Methyl-3-tetrahydrofuranthiol, and the molecular formula is C7H7ClN2S, Category: tetrahydrofurans.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Zhu, Jiayi published the artcileNiSO₄-catalyzed C-H activation/C-S cross-coupling of 1,2,3-triazole N-oxides with thiols, Computed Properties of 57124-87-5, the publication is Organic & Biomolecular Chemistry (2015), 13(12), 3711-3720, database is CAplus and MEDLINE.

An efficient nickel-catalyzed protocol for C-S cross-coupling through the direct functionalization of 2-aryl-1,2,3-triazole N-oxide C-H bonds with aryl or alkyl thiols, or di-Ph disulfide has been developed. The targeted N⁺-O^– bond cleavage can be observed during the reaction, and thus obviates the need to use an addnl. deoxygenation step. This new protocol for the preparation of thiolated 2-aryl-1,2,3-triazoles, e.g., I, appears to offer good yields with high regioselectivity, mild conditions, and a wide substrate scope.

Organic & Biomolecular Chemistry published new progress about 57124-87-5. 57124-87-5 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Thiol, name is 2-Methyl-3-tetrahydrofuranthiol, and the molecular formula is C18H26ClN3O, Computed Properties of 57124-87-5.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Choi, Jae-Wook published the artcileFeasibility of Laminaria japonica as a feedstock for fast pyrolysis in a bubbling fluidized-bed reactor, Recommanded Product: 3-Hydroxydihydrofuran-2(3H)-one, the publication is Journal of Analytical and Applied Pyrolysis (2015), 141-149, database is CAplus.

Laminaria japonica, brown algae, was used as a feedstock for fast pyrolysis in a bubbling fluidized-bed (BFB) reactor by manipulating the pyrolysis temperature, feeding rate, and ratio of the fluidizing velocity to the min. fluidizing velocity (U/U_mf), which exhibited optimum operating conditions of a feeding rate of 600 g/h, a U/U_mf of 18.3 and a pyrolysis temperature of 425°C. The maximum yield of L. japonica-derived bio-oil (approx. 35 weight %) was lower than that of lignocellulose. When fractionated, the L. japonica-derived bio-oil was found to be composed of several major compounds, including cyclic aliphatic compounds, which were very different from aromatic mols., the major compounds of lignocellulose-derived bio-oil.

Journal of Analytical and Applied Pyrolysis published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Recommanded Product: 3-Hydroxydihydrofuran-2(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Condurso, Concetta published the artcileStability of powdered infant formula during secondary shelf-life and domestic practices, SDS of cas: 19444-84-9, the publication is International Dairy Journal (2020), 104761, database is CAplus.

Powd. infant formula (PIF) and lactose-free PIF during secondary shelf-life (SSL) and under domestic practices was investigated to verify their stability up to the expiration date and under the label instructions for milk reconstitution. Particular attention was given to variations in Maillard reaction and lipid peroxidation products identified and quantified by HS-SPME-GC-MS. Two types of PIF: Type A based on bovine milk and Type B a lactose-free product based on glucose syrup were analyzed. The PIF were analyzed at regular time intervals beyond the labeled expiration date after opening, and reconstituted using water at 70°C, 80°C and 90°C. A large number of volatile compounds were identified and significant statistically differences resulted during SSL and water temperature used for reconstitution that were correlated to the PIF composition The study showed that water temperature for reconstitution of samples and the SSL has to be adapted to PIF composition

International Dairy Journal published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, SDS of cas: 19444-84-9.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Spanik, Ivan published the artcileClassification of wine distillates using multivariate statistical methods based on their direct GC-MS analysis, Recommanded Product: 3-Hydroxydihydrofuran-2(3H)-one, the publication is Chemical Papers (2015), 69(3), 395-401, database is CAplus.

This work describes a novel methodol. for the recognition of brandies based on direct injection of a raw sample followed by GC-MS anal. Direct injection was chosen for its simplicity and the fact that the composition of the samples analyzed remains unchanged compared to original brandy. The repeatability of the anal. procedure was evaluated by a comparison of the peak areas for randomly selected compounds obtained from 10 parallel measurements. A novel chemometric procedure was investigated in order to sep. the samples studied on the basis of their geog. origin, processing technol. or maturation time. In this procedure, a principal component anal. was applied to full chromatograms to select the time interval that shows the significant differences between the samples studied. It was shown that the chromatogram recorded at 36-39 min bore the maximal differences, hence it could be used to classify the brandy samples. The chromatog. peaks found within this time interval were identified and their peak areas determined These compounds could be used as specific markers for determining geog. origin or processing technol.

Chemical Papers published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C8H17Br, Recommanded Product: 3-Hydroxydihydrofuran-2(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Silveira, Marcello R. published the artcileGuava-flavored whey beverage processed by cold plasma technology: Bioactive compounds, fatty acid profile and volatile compounds, Quality Control of 19444-84-9, the publication is Food Chemistry (2019), 120-127, database is CAplus and MEDLINE.

The effect of cold plasma processing time and gas flow on bioactive compounds such as vitamin C, carotenoids and phenolic compounds, DPPH, angiotensin-converting-enzyme (ACE) inhibitory activity, fatty acids profile, and volatile compounds of guava-flavored whey beverage was investigated. For comparative purposes, a pasteurized beverage was also manufactured Cold plasma increased the concentration of bioactive and volatile compounds, and proportionated changes in the fatty acids profile. The milder conditions like lower flow rate and processing time, resulted in higher vitamin C and volatile compounds levels, and higher antioxidant activity, but with a lower carotenoids content and a less favorable fatty acids profile. More drastic conditions like higher flow rate and processing time resulted in products with lower vitamin C and volatile compounds levels, but with higher carotenoids content and ACE inhibitory activity. It can be concluded that the cold plasma processing can improve the properties of the guava-flavored whey beverages (increased concentration of bioactive and volatile compounds), while the effect on the fatty acid profile and ACE inhibitory activity is dependent on the process parameters (processing time and flow rate).

Food Chemistry published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C10H16Br3N, Quality Control of 19444-84-9.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem