Tag: M.W=100-150

Quintanilla-Casas, Beatriz published the artcileThiols in brewed coffee: Assessment by fast derivatization and liquid chromatography-high resolution mass spectrometry, Safety of 2-Methyl-3-tetrahydrofuranthiol, the publication is LWT–Food Science and Technology (2015), 64(2), 1085-1090, database is CAplus.

In the present paper, we present a simple, reliable, selective and sensitive method for the identification and quantification of volatile thiols at trace levels in coffee brews. A simultaneous derivatization/extraction procedure followed by liquid chromatog.-electrospray high-resolution mass spectrometry is proposed and adapted to coffee brew matrix, and the performance of the method is evaluated. The linearity, sensitivity, recovery and both the intra-day and inter-day accuracy were all satisfactory. According to established identification criteria, seven target and nine non-target thiols were identified and quantified in coffee brew samples. Several of them are reported here for the first time in coffee brews, and our results are in agreement with previously reported results for coffee powder analyzed using similar anal. approach.

LWT–Food Science and Technology published new progress about 57124-87-5. 57124-87-5 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Thiol, name is 2-Methyl-3-tetrahydrofuranthiol, and the molecular formula is C5H10OS, Safety of 2-Methyl-3-tetrahydrofuranthiol.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Dayaker, Gandrath published the artcileA Versatile and Stereocontrolled Total Synthesis of Dihydroxylated Docosatrienes Containing a Conjugated E,E,Z-Triene, Name: 3-Hydroxydihydrofuran-2(3H)-one, the publication is Chemistry – A European Journal (2014), 20(10), 2879-2887, database is CAplus and MEDLINE.

A versatile strategy featuring a Colvin rearrangement, hydrozirconation, a Sonogashira cross-coupling reaction and a (Z)-selective Wittig olefination, was successfully developed for the construction of a conjugated E,E,Z-triene subunit, flanked on both sides by two (Z)-allylic hydroxy-groups. This chem. pattern is found in many endogenous lipid metabolites such as maresin 1 (MaR1), neuroprotectin D1 (NPD1) and its aspirin triggered-isomer AT-NPD1, which not only counter-regulate inflammation but also actively orchestrate (at nanomolar doses) the resolution and termination program of acute inflammation while promoting wound healing, return to homeostasis and neuroprotection. Unlike previous approaches, the advantages of the present strategy are obvious, as it allows a modification of a nonpolar tail, the carboxylated head or both ends of the mol. without repeating the whole synthetic sequence (about 26-34 steps according to the literature). Thus, the first total synthesis of NPD1 Me ester epimer (which can also be considered as an enantiomer of AT-NPD1) and its n-3 docosapentaenoic acid derived analog were achieved from a highly functionalized and late advanced pivotal intermediate. This innovative route may be easily adapted to gain access to other dihydroxylated metabolites and analogs of polyunsaturated fatty acids containing a conjugated E,E,Z-triene subunit. Different epimers/diastereoisomers may be obtained by purchasing the suitable optically pure (S)- and/or (R)-1,2,4-butanetriol derivatives as a chiral pool for both stereogenic centers. The tilte compound thus formed included (4Z,7Z,10S,11E,13E,15Z,17S,19Z)-10,17-dihydroxy-4,7,11,13,15,19-docosahexaenoic acid Me ester (I) which is an epimer of neuroprotectin-D1 Me ester and (7Z,10S,11E,13E,15Z,17S,19Z)-10,17-Dihydroxy-7,11,13,15,19-docosapentaenoic acid Et ester which is an omega-3 docosapentaenoic acid (n-3 DPA) analog.

Chemistry – A European Journal published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Name: 3-Hydroxydihydrofuran-2(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

De Clercq, Rik published the artcileConfinement Effects in Lewis Acid-Catalyzed Sugar Conversion: Steering Toward Functional Polyester Building Blocks, Category: tetrahydrofurans, the publication is ACS Catalysis (2015), 5(10), 5803-5811, database is CAplus.

We report the use of solid Lewis acid catalysts for the conversion of tetrose sugars to four-carbon α-hydroxy acid esters (C₄-AHA), which are useful as functional polyester building blocks. Sn-β was by far the most active and selective catalyst, yielding up to 80% Me vinyl glycolate (MVG), methyl-4-methoxy-2-hydroxybutanoate (MMHB), and α-hydroxy-γ-butyrolactone (HBL) combined at 95% conversion. A very high turnover frequency (TOF) of 330 mol_C4-AHA mol_Sn h^-1 was attained using Sn-β, a more than 6-fold increase compared with homogeneous SnCl₄·5H₂O. It is shown that, using different Sn-based catalysts with various pore sizes, the product distribution is strongly dependent on the size of the catalyst pores. Catalysts containing mainly mesopores, such as Sn-MCM-41 or Sn-SBA-15, prefer the production of the more bulky MMHB, whereas microporous catalysts such as Sn-β or Sn-MFI favor the production of MVG. This effect can be further enhanced by increasing the reaction temperature At 363 K, only 20% MVG is attained using Sn-β, but at 433 K, this increases to 50%. Using a kinetic anal., it was found that, in microporous catalysts, steric hindrance near the Sn active site in the catalyst pores plays a dominant role in favoring the reaction pathway toward MVG. Moreover, the selectivity toward both products is kinetically controlled.

ACS Catalysis published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Category: tetrahydrofurans.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Ali, Khursheed published the artcileAloe vera extract functionalized zinc oxide nanoparticles as nanoantibiotics against multi-drug resistant clinical bacterial isolates, Recommanded Product: 3-Hydroxydihydrofuran-2(3H)-one, the publication is Journal of Colloid and Interface Science (2016), 145-156, database is CAplus and MEDLINE.

ZnO nanoparticles (ZnONPs) were synthesized through a simple and efficient biogenic synthesis approach, exploiting the reducing and capping potential of Aloe barbadensis Miller (A. vera) leaf extract (ALE). ALE-capped ZnO nanoparticles (ALE-ZnONPs) were characterized using UV-Vis spectroscopy, x-ray diffraction (x-ray diffraction), Fourier transform IR (FTIR) spectroscopy, SEM, energy dispersive x-ray spectroscopy (EDX), and TEM analyses. X-ray diffraction anal. provided the average size of ZnONPs as 15 nm. FTIR spectral anal. suggested the role of phenolic compounds, terpenoids and proteins present in ALE, in nucleation and stability of ZnONPs. Flow cytometry and at. absorption spectrophotometry (AAS) data analyses revealed the surface binding and internalization of ZnONPs in Gram +ve (Staphylococcus aureus) and Gram -ve (Escherichia coli) cells, resp. Significant antibacterial activity of ALE-ZnONPs was observed against extended spectrum beta lactamases (ESBL) pos. E. coli, Pseudomonas aeruginosa, and methicillin resistant S. aureus (MRSA) clin. isolates exhibiting the MIC and MBC values of 2200, 2400 μg/mL and 2300, 2700 μg/mL, resp. Substantial inhibitory effects of ALE-ZnONPs on bacterial growth kinetics, exopolysaccharides and biofilm formation, unequivocally suggested the antibiotic and antibiofilm potential. Overall, the results elucidated a rapid, environmentally benign, cost-effective, and convenient method for ALE-ZnONPs synthesis, for possible applications as nanoantibiotics or drug carriers.

Journal of Colloid and Interface Science published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Recommanded Product: 3-Hydroxydihydrofuran-2(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Eltayeb, Ikram Mohamed published the artcileComparative study of chemical composition of Acacia seyal stem, stem wood and stem bark dry distillates used by sudaneses women as cosmetic and medicine, Synthetic Route of 19444-84-9, the publication is International Journal of Pharmacy and Pharmaceutical Sciences (2017), 9(11), 218-224, database is CAplus.

The content and chem. composition of dry distillates of the stem, stem wood and stem bark of Acacia seyal were investigated. The distillates are fumigants of A. seyal locally known in Sudan as Dokhan and widely used for its cosmetic, aromatic and medicinal value for the treatment of candidiasis, genital yeast infection, urinary tract infection, diarrhoea, respiratory tract infection, skin infection and with potent, antioxidant and antimicrobial activities. The dry distillates were prepared by dry distillation method from the Acacia seyal stem, stem wood and stem bark and investigated chem. by GC-MS anal. GC-MS anal. revealed the presence of one hundred and 23 constituents in the stem distillate with major constituents of solerone, furfural, catechol, syringol, allo-inositol, mequinol, furfuralc., 3-methyl-1,2-cyclopentanedione, phenol, homovanillyl alc. and 3-cresol. the wood distillate show detection of eighty compounds, with main 1, 3-dimethyl-5-methoxypyrazol, syringol, furfuralc., mequinol, 1,2-anhydro-3,4,5,6-alloinositol, 3-methyl-1,2-cyclopentanedione, catechol, 3-methoxycatechol, homovanillyl alc., homosyringic acid, 3-cresol, 3-methyl-2-cyclopentenone and 1,2-cyclopentanedione. Sixty six compounds were detected in the distillate bark and the main compounds were found to be hexadecanoic, catechol, tetrapentacontane, phenol, mequinol and 2-ethylfurane. The result concludes that the medicinal Sudanese Dokhan have good potential as sources of different bioactive compounds and antioxidants.

International Journal of Pharmacy and Pharmaceutical Sciences published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Synthetic Route of 19444-84-9.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Savareear, Benjamin published the artcileNon-targeted analysis of the particulate phase of heated tobacco product aerosol and cigarette mainstream tobacco smoke by thermal desorption comprehensive two-dimensional gas chromatography with dual flame ionisation and mass spectrometric detection, Quality Control of 19444-84-9, the publication is Journal of Chromatography A (2019), 327-337, database is CAplus and MEDLINE.

An anal. methodol. based on thermal desorption and comprehensive two-dimensional gas chromatog. with dual time-of-flight mass spectrometry and flame ionization detection (TD-GC × GC-TOFMS/FID) was developed for non-target anal. of volatile organic compounds (VOCs). The technique was optimized for the measurement of the VOC content of the particulate phase (PP) fraction of aerosols produced by a tobacco heating product (THP1.0) and 3R4F mainstream tobacco smoke (MTS). The method involves sampling the PP fraction on quartz wool packed in a sorbent tube directly connected to machine-puffing, followed by a dilution through a TD recollection procedure over Tenax/Sulficarb sorbent before TD-GC × GC-TOFMS/FID anal. The comparison of the VOC content of the PP fraction of aerosols produced by THP1.0 and MTS highlighted the compositional difference between tobacco combustion (592 peaks) and tobacco heating process (160 peaks). Mass spectrometric signals were used for qual. analyses based on linear retention indexes, mass spectral matches, and GC × GC structured chromatograms, which collectively identified up to 90% of analytes detected in PP samples. FID signals were used for semi-quant. analyses based on a chem. class external calibration method. The global chem. composition of PP samples showed that hydrocarbons, oxygenated, and nitrogen-containing compounds were fewer in number and much less abundant in THP1.0 PP. Overall, 93 compounds were common to the two sample types. Excepted for a few highly volatile compounds (mainly furan family) as well as glycerin and its acetate, analyte concentrations were higher in MTS PP.

Journal of Chromatography A published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Quality Control of 19444-84-9.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Li, Xiaoman published the artcileCatalyst- and Metal-Free Photo-Oxidative Coupling of Thiols with BrCCl₃, HPLC of Formula: 57124-87-5, the publication is European Journal of Organic Chemistry (2022), 2022(23), e202200340, database is CAplus.

This paper reported a catalyst- and metal-free method to construct disulfide bond with BrCCl₃ under light irradiation This clean and mild reaction promoted the oxidative coupling of thiols with wide substrate scope, and was applicable to benzylic, aryl and aliphatic thiols, especially cysteine derivative The disulfides were obtained in high yields up to 98%, avoiding the use of heating, strong oxidant, metal reagent or catalyst. This facile strategy facilitated the synthesis of disulfide compounds

European Journal of Organic Chemistry published new progress about 57124-87-5. 57124-87-5 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Thiol, name is 2-Methyl-3-tetrahydrofuranthiol, and the molecular formula is C5H10OS, HPLC of Formula: 57124-87-5.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Wang, Wenli published the artcileAnalysis of volatile compounds in Chinese dry-cured hams by comprehensive two-dimensional gas chromatography with high-resolution time-of-flight mass spectrometry, COA of Formula: C4H6O3, the publication is Meat Science (2018), 14-25, database is CAplus and MEDLINE.

A microwave assisted extraction method coupled with solvent assisted flavor evaporation (MAE-SAFE) was used to extract the volatiles from three-selected Chinese dry-cured hams (Jinhua ham, Xuanwei ham and Rugao ham). Extracts were analyzed by comprehensive two-dimensional gas chromatog. with high-resolution time-of-flight mass spectrometry (GC × GC/HR-TOFMS), gas chromatog.-mass spectrometry (GC-MS), resp. A total 165 volatile compounds were identified by GC × GC/HR-TOFMS while only 50 compounds were identified by GC-MS. Principal component anal. showed that the specific dominant volatile compounds were [S-(R*,R*)]-2,3-butanediol (26.39%) and 3-methyl-butanoic acid (7.53%) for Jinhua ham, were [R-(R*,R*)]-2,3-butanediol (16.85%) and acetic acid (8.25%) for Rugao ham and were dihydro-4-hydroxy-2(3H)-furanone (11.67%) and hexanoic acid (8.24%) for Xuanwei ham. The results not only provided a fast and mild extraction method to analyze the volatiles in non-volatile food matrixes, but also represented the detailed information of volatile profiles of Chinese dry-cured hams.

Meat Science published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C20H18BrN3, COA of Formula: C4H6O3.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Makibar, Jon published the artcilePerformance of a conical spouted bed pilot plant for bio-oil production by poplar flash pyrolysis, Product Details of C4H6O3, the publication is Fuel Processing Technology (2015), 283-289, database is CAplus.

Poplar (Populus nigra) flash pyrolysis has been performed at the IK4-Ikerlan 25 kg h^– 1 pilot plant equipped with a conical spouted bed reactor. Gas, bio-oil and char yields and properties have been studied in the 425-525 °C range. This reactor has been proven to be especially suitable for this process as high bio-oil yields have been obtained, with the maximum being 69 weight% at 455 °C. The bio-oil has been collected in two fractions: the lighter one, which accounts for 85 weight% of the bio-oil, has a high water content and is composed mainly of acids and ketones, whereas the heavier fraction has a lower water content and is rich in phenols. These fractions are miscible, obtaining a bio-oil with a water content lower than 25 weight% and a higher heating value in the 16-18 MJ kg^– 1 range.

Fuel Processing Technology published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Product Details of C4H6O3.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Rayne, Sierra published the artcilepH dependent partitioning behaviour of food and beverage aroma compounds between air-aqueous and organic-aqueous matrices, Synthetic Route of 57124-87-5, the publication is Flavour and Fragrance Journal (2016), 31(3), 228-234, database is CAplus.

Aroma compounds in the Flavornet database were screened for ionizable functional groups such as carboxylic acids, aliphatic and aromatic amines, phenols, alcs. and thiols. Of the 738 aroma compounds listed in this database, 101 mols. have ionizable moieties with estimated monomeric aqueous pK_a values ranging between 1.75 and 10.97. pH dependent effective air/water partitioning coefficients (K_aw,eff) and n-octanol/water partitioning coefficients (D_ow) were estimated for all ionizable aroma compounds over the pH range from 0 to 14. The ionizable aroma compounds display a broad range of K_aw,eff (1.8 × 10^-23 to 6.1 atm M^-1) and log D_ow (-6.2 to +7.2 units) values. For many aroma compounds, pH dependent ionization will have a significant effect on K_aw,eff and D_ow, leading to variations in these physico-chem. properties by up to 11 orders of magnitude over the composite pH range of common foods and beverages. Changes in food and beverage pH affect not only the relative contributions of neutral vs. charged forms of ionizable aroma compounds (which directly affects analyte volatility and olfactory reception), but also partitioning between freely dissolved and sorbed forms of the analyte in solution (which indirectly affects analyte volatility). Copyright © 2015 John Wiley & Sons, Ltd.

Flavour and Fragrance Journal published new progress about 57124-87-5. 57124-87-5 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Thiol, name is 2-Methyl-3-tetrahydrofuranthiol, and the molecular formula is C5H10OS, Synthetic Route of 57124-87-5.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem