Ohtsuka, Eiko’s team published research in Chemical & Pharmaceutical Bulletin in 31 | CAS: 87865-78-9

Chemical & Pharmaceutical Bulletin published new progress about 87865-78-9. 87865-78-9 belongs to tetrahydrofurans, auxiliary class Nucleosides and Nucleotides,Nucleoside Analogues, name is N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, and the molecular formula is C26H45N5O7Si2, Recommanded Product: N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide.

Ohtsuka, Eiko published the artcileStudies on transfer ribonucleic acids and related compounds. XLIV. A large-scale synthesis of the anticodon heptanucleotide of formyl-methionine transfer ribonucleic acid by using 2′-O-tetrahydrofuranylnucleosides, Recommanded Product: N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, the publication is Chemical & Pharmaceutical Bulletin (1983), 31(6), 1910-16, database is CAplus and MEDLINE.

2′-O-Tetrahydrofuranyl nucleosides were prepared by an improved procedure via 3′,5′-tetraisopropyldisiloxanyl nucleosides. A large-scale synthesis of the anticodon heptanucleotide C-U-C-A-U-A-A of Escherichia coli formylmethionine tRNA was performed by the phosphotriester method involving condensation of oligonucleotides having 2′-O-tetrahydrofuranyl protecting groups.

Chemical & Pharmaceutical Bulletin published new progress about 87865-78-9. 87865-78-9 belongs to tetrahydrofurans, auxiliary class Nucleosides and Nucleotides,Nucleoside Analogues, name is N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, and the molecular formula is C26H45N5O7Si2, Recommanded Product: N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Van de Vyver, Stijn’s team published research in ACS Catalysis in 5 | CAS: 19444-84-9

ACS Catalysis published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C21H26Br4S2, Name: 3-Hydroxydihydrofuran-2(3H)-one.

Van de Vyver, Stijn published the artcileSolid Lewis Acids Catalyze the Carbon-Carbon Coupling between Carbohydrates and Formaldehyde, Name: 3-Hydroxydihydrofuran-2(3H)-one, the publication is ACS Catalysis (2015), 5(2), 972-977, database is CAplus.

The development of catalytic C-C bond formation schemes based on renewable substrates is important for defining sustainable paradigms for chem. manufacturing With a few exceptions, aldol condensation reactions between biomass-derived platform chems. have received little attention so far. Here the C-C coupling between 1,3-dihydroxyacetone (DHA) and formaldehyde into α-hydroxy-γ-butyrolactone (HBL) using Sn-Beta is demonstrated. Reactivity studies, coupled with spectroscopic and computational analyses, show that the formation of HBL proceeds by soft enolization of DHA followed by an aldol addition of formaldehyde to the Sn-enolate intermediate, generating erythrulose as an intermediate species. Isotopic labeling is used to reveal the position where formaldehyde is incorporated into HBL, providing further support for our proposed mechanism. Finally, combining the C-C coupling reaction with transfer hydrogenation of formaldehyde has allowed us to expand the substrate scope to include polyols glycerol and ethylene glycol.

ACS Catalysis published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C21H26Br4S2, Name: 3-Hydroxydihydrofuran-2(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Hayashi, Junsuke’s team published research in Bioorganic & Medicinal Chemistry in 26 | CAS: 87865-78-9

Bioorganic & Medicinal Chemistry published new progress about 87865-78-9. 87865-78-9 belongs to tetrahydrofurans, auxiliary class Nucleosides and Nucleotides,Nucleoside Analogues, name is N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, and the molecular formula is C26H45N5O7Si2, Name: N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide.

Hayashi, Junsuke published the artcileSyntheses of prodrug-type 2′-O-methyldithiomethyl oligonucleotides modified at natural four nucleoside residues and their conversions into natural 2′-hydroxy oligonucleotides under reducing condition, Name: N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, the publication is Bioorganic & Medicinal Chemistry (2018), 26(22), 5838-5844, database is CAplus and MEDLINE.

We previously reported that reducing-environment-responsive prodrug-type small interfering RNA (siRNA) bearing 2′-O-methyldithiomethyl (2′-O-MDTM) uridine exhibits efficient knockdown activity and nuclease resistance. In this report, we describe the preparation of 2′-O-MDTM oligonucleotides modified not only at uridine but also at adenosine, guanosine and cytidine residues by post-synthetic modification. Precursor oligonucleotides bearing 2′-O-(2,4,6-trimethoxybenzylthiomethyl) (2′-O-TMBTM) adenosine, guanosine, and cytidine were reacted with dimethyl(methylthio)sulfonium tetrafluoroborate to form 2′-O-MDTM oligonucleotides in the same manner as the oligonucleotide bearing 2′-O-TMBTM uridine. Furthermore, the oligonucleotides bearing 2′-O-MDTM adenosine, guanosine, and cytidine were efficiently converted into corresponding natural 2′-hydroxy oligonucleotides under the cytosol-mimetic reducing condition.

Bioorganic & Medicinal Chemistry published new progress about 87865-78-9. 87865-78-9 belongs to tetrahydrofurans, auxiliary class Nucleosides and Nucleotides,Nucleoside Analogues, name is N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, and the molecular formula is C26H45N5O7Si2, Name: N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Markiewicz, Wojciech T.’s team published research in Nucleosides & Nucleotides in 17 | CAS: 87865-78-9

Nucleosides & Nucleotides published new progress about 87865-78-9. 87865-78-9 belongs to tetrahydrofurans, auxiliary class Nucleosides and Nucleotides,Nucleoside Analogues, name is N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, and the molecular formula is C26H45N5O7Si2, Safety of N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide.

Markiewicz, Wojciech T. published the artcileStudies on synthesis and structure of O-β-D-ribofuranosyl(1”→2′)ribonucleosides and oligonucleotides, Safety of N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, the publication is Nucleosides & Nucleotides (1998), 17(1-3), 411-424, database is CAplus.

Minor nucleosides found in several eukaryotic initiator tRNAs1Met, O-β-D-ribofuranosyl(1”→2′)adenosine and -guanosine (Ar and Gr), as well as their pyrimidine analogs, were obtained from N-protected 3′,5′-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)ribonucleosides and 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose in the presence of tin tetrachloride in 1,2-dichloroethane. A crystal structure has been solved for 2′-O-ribosyluridine. The 3′-phosphoramidites of protected 2′-O-ribosylribonucleosides were prepared as the reagents for 2′-O-ribofuranosyloligonucleotides synthesis. O-β-D-Ribofuranosyl(1”→2′)adenylyl(3’→5′)guanosine (ArpG) was obtained and its structure was analyzed by NMR spectroscopy.

Nucleosides & Nucleotides published new progress about 87865-78-9. 87865-78-9 belongs to tetrahydrofurans, auxiliary class Nucleosides and Nucleotides,Nucleoside Analogues, name is N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, and the molecular formula is C26H45N5O7Si2, Safety of N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Sekine, Mitsuo’s team published research in Nucleosides & Nucleotides in 11 | CAS: 87865-78-9

Nucleosides & Nucleotides published new progress about 87865-78-9. 87865-78-9 belongs to tetrahydrofurans, auxiliary class Nucleosides and Nucleotides,Nucleoside Analogues, name is N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, and the molecular formula is C15H24S, Computed Properties of 87865-78-9.

Sekine, Mitsuo published the artcileSynthesis of adenosine, guanosine and cytidine monomer building units bearing the [[2-(methylthio)phenyl]thio]methyl (MPTM) group as the 2′-hydroxyl protecting group, Computed Properties of 87865-78-9, the publication is Nucleosides & Nucleotides (1992), 11(2-4), 679-91, database is CAplus.

A new 2′-hydroxyl protecting group, [[2-(methylthio)phenyl]thio]methyl (MPTM), was introduced into the 2′-position of adenosine, guanosine and cytidine building units required for the synthesis of oligoribonucleotides.

Nucleosides & Nucleotides published new progress about 87865-78-9. 87865-78-9 belongs to tetrahydrofurans, auxiliary class Nucleosides and Nucleotides,Nucleoside Analogues, name is N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, and the molecular formula is C15H24S, Computed Properties of 87865-78-9.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Kulikova, Irina V.’s team published research in ARKIVOC (Gainesville, FL, United States) in | CAS: 87865-78-9

ARKIVOC (Gainesville, FL, United States) published new progress about 87865-78-9. 87865-78-9 belongs to tetrahydrofurans, auxiliary class Nucleosides and Nucleotides,Nucleoside Analogues, name is N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, and the molecular formula is C26H45N5O7Si2, Safety of N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide.

Kulikova, Irina V. published the artcileEffective isomerization of 3′,5′-O-(tetraisopropyldisiloxane-1,3-di-yl)nucleosides in the presence of trimethylsilyl trifluoromethanesulfonate, Safety of N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, the publication is ARKIVOC (Gainesville, FL, United States) (2008), 158-170, database is CAplus.

Trimethylsilyl trifluoromethanesulfonate catalyze effective isomerization of 3′,5′-O-(tetraisopropyldisiloxane-1,3-di-yl)nucleosides, e.g. I, in 1,2-dichloroethane at 0°C into 2′,3′-O-(tetraisopropyldisiloxane-1,3-di-yl)-derivatives, e.g. II, which can be obtained in 55-90% yields. On the other hand 3′,5′-O-(tetraisopropyldisiloxane-1,3-di-yl) nucleosides, e.g. I, were stable in the presence of tin tetrachloride. Only in the case of uridine derivative I a substantial amount of isomerization product II was formed.

ARKIVOC (Gainesville, FL, United States) published new progress about 87865-78-9. 87865-78-9 belongs to tetrahydrofurans, auxiliary class Nucleosides and Nucleotides,Nucleoside Analogues, name is N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, and the molecular formula is C26H45N5O7Si2, Safety of N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Yamaguchi, Sho’s team published research in Chemical Communications (Cambridge, United Kingdom) in 50 | CAS: 19444-84-9

Chemical Communications (Cambridge, United Kingdom) published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C14H10O4S2, Category: tetrahydrofurans.

Yamaguchi, Sho published the artcileTin-catalyzed conversion of biomass-derived triose sugar and formaldehyde to α-hydroxy-γ-butyrolactone, Category: tetrahydrofurans, the publication is Chemical Communications (Cambridge, United Kingdom) (2014), 50(35), 4600-4602, database is CAplus and MEDLINE.

The direct conversion of biomass-derived 1,3-dihydroxyacetone (DHA) and formaldehyde to α-hydroxy-γ-butyrolactone (HBL) was achieved through the use of tin(iv) chloride and a small amount of water and the yield reached up to 70%. The reaction mechanism was also investigated by incorporating d2-formaldehyde into the reaction mixtures

Chemical Communications (Cambridge, United Kingdom) published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C14H10O4S2, Category: tetrahydrofurans.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Moity, Laurianne’s team published research in Green Chemistry in 16 | CAS: 19444-84-9

Green Chemistry published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, COA of Formula: C4H6O3.

Moity, Laurianne published the artcileIn silico design of bio-based commodity chemicals: application to itaconic acid based solvents, COA of Formula: C4H6O3, the publication is Green Chemistry (2014), 16(1), 146-160, database is CAplus.

Global issues are deeply changing the face of the chem. industry. Both the feedstock – biomass vs. oil – and the chem. transformations used are now chosen to comply with a sustainable development. In this work, a computer-assisted organic synthesis program, named GRASS (GeneratoR of Agro-based Sustainable Solvents), is proposed to help in the design of sustainable solvents from biomass feedstock. A careful selection of industrially relevant chem. transformations was performed to propose a set that allows obtaining in a few steps (1 to 3) a large number of commodity chems. from a chosen set of bio-based building-blocks. Emphasis was put on solvents since this type of compound is undergoing a deep renewal due to more stringent regulatory constraints, but the same approach may be extended to other commodity chems. This methodol. was exemplified starting from itaconic acid, a multifunctional bio-based building block. We checked a posteriori that all itaconic acid based-solvents reported in the literature do indeed belong to the set of virtual solvents generated by GRASS, along with an extended list of new derivatives that could be of potential interest.

Green Chemistry published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, COA of Formula: C4H6O3.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Polina, I. N.’s team published research in Izvestiya Vysshikh Uchebnykh Zavedenii, Khimiya i Khimicheskaya Tekhnologiya in 65 | CAS: 19444-84-9

Izvestiya Vysshikh Uchebnykh Zavedenii, Khimiya i Khimicheskaya Tekhnologiya published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, COA of Formula: C4H6O3.

Polina, I. N. published the artcileInvestigation of the component composition of the oxidative thermal degradation products of fuel pellets from the Heracleum sosnowskyi Manden biomass by chromatography-mass-spectrometry, COA of Formula: C4H6O3, the publication is Izvestiya Vysshikh Uchebnykh Zavedenii, Khimiya i Khimicheskaya Tekhnologiya (2022), 65(5), 68-76, database is CAplus.

The component composition of oxidative thermal degradation products of Heracleum sosnowskyi Manden biomass was studied by chromatog.-mass-spectrometry. The hogweed Sosnovskyi biomass was collected on the territory of the village of Vylgort in the Komi Republic, dried to an atm.-dry state, crushed to dm < 0.25 mm and pressed with a force of 10 kN. Fuel pellets were burned in the special device. The products of oxidative thermal degradation were captured and analyzed on a gas-liquid chromatog. with a mass-selective detector. As a result of mass spectrums anal., 39 low-mol.-weight products with a retention time of 6 to 79 min and a percentage content of 0.4 to 12% were identified from 47 captured compounds Qual. and quant. anal. of the component composition of the degradation products showed that their formation is directly related to the component composition of the biomass and is determined by the content of cellulose, hemicellulose and lignin. Anal. of data on retention time of the degradation products showed that cellulose and hemicellulose of the biomass sample are degraded priority, while lignin is thermally more stable due to its aromatic nature. Anal. of data on products of oxidative thermal degradation showed that in mass terms, polysaccharides and lignin are formed as a percentage 45 and 49 resp., while the composition of the products of destruction of polysaccharides is more diverse (23 and 16 names). It is shown that the list of products of oxidative thermal degradation of the Heracleum sosnowskyi Manden biomass is comparable to the products of thermal decomposition of lignocellulosic materials of other botanical origin. The results of the presented study can be used in the calculation of processes and installations for burning fuel pellets from the biomass of the Heracleum sosnowskyi Manden or a combined composition fuel pellets. As well as the results can be used to assess the complex environmental impact of the technol. of the energy use of the biomass of the hogweed Sosnowskyi on the atm. air.

Izvestiya Vysshikh Uchebnykh Zavedenii, Khimiya i Khimicheskaya Tekhnologiya published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, COA of Formula: C4H6O3.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Bobkov, Georgii V.’s team published research in Tetrahedron in 64 | CAS: 87865-78-9

Tetrahedron published new progress about 87865-78-9. 87865-78-9 belongs to tetrahydrofurans, auxiliary class Nucleosides and Nucleotides,Nucleoside Analogues, name is N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, and the molecular formula is C26H45N5O7Si2, Recommanded Product: N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide.

Bobkov, Georgii V. published the artcilePhosphoramidite building blocks for efficient incorporation of 2′-O-aminoethoxy(and propoxy)methyl nucleosides into oligonucleotides, Recommanded Product: N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, the publication is Tetrahedron (2008), 64(27), 6238-6251, database is CAplus.

A simple and efficient method for the preparation of eight phosphoramidite building blocks for incorporation of 2′-O-(2-aminoethoxymethyl)ribonucleosides and 2′-O-(3-aminopropoxymethyl)ribonucleosides into synthetic oligonucleotides has been developed. The synthetic routes are maximally convergent and provide sufficient amounts of phosphoramidites for several solid-phase synthesis coupling reactions. Using acyclic derivatives, e.g., AcOCH2CH2OCH2CH2NHCOCF3 the overall yields of phosphoramidites, e.g. I, were increased up to 50% for pyrimidine nucleosides and up to 30% for purine derivatives with substantial decrease of total reaction steps. The 2′-O-substituent was found to be stable during oligonucleotide synthesis. The resulting oligonucleotides are of particular interest for post-synthetic functionalization and conjugation.

Tetrahedron published new progress about 87865-78-9. 87865-78-9 belongs to tetrahydrofurans, auxiliary class Nucleosides and Nucleotides,Nucleoside Analogues, name is N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, and the molecular formula is C26H45N5O7Si2, Recommanded Product: N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem