Heterocyclic Building Blocks-Tetrahydrofuran

Wang, Chenguang; Liu, Yong; Cui, Zhibing; Yu, Xiaohu; Zhang, Xinghua; Li, Yuping; Zhang, Qi; Chen, Lungang; Ma, Longlong published the artcile< In Situ Synthesis of Cu Nanoparticles on Carbon for Highly Selective Hydrogenation of Furfural to Furfuryl Alcohol by Using Pomelo Peel as the Carbon Source>, Recommanded Product: (Tetrahydrofuran-2-yl)methanol, the main research area is copper nanoparticle carbon hydrogenation furfural furfuryl alc.

A facile approach was developed to directly synthesize carbon-supported metal nanoparticles with pomelo peel as the carbon source and metal nitrate solution as the metal source. Fe/C, Co/C, Ni/C, and Cu/C catalysts were prepared after calcination in N2 without further reduction The metal nanoparticles and formation mechanism were investigated by multiple techniques such as XRD, HRTEM, XPS, FTIR spectra, SEM, and TG-MS thermal anal. In the case of furfural hydrogenation, Cu/C catalyst exhibited the best activity and exclusive selectivity to produce furfuryl alc. with complete conversion, and excellent selectivity can be maintained at a higher temperature of 240°C. The particle size of Cu nanoparticles can be tuned by the calcination temperature and metal loading for improving catalytic activity. The excellent performance of Cu nanoparticles was also studied by d. functional theory calculation, agreeing well with the experiments A green and facile approach to in situ synthesis of metal nanoparticles on carbon for exclusively selective hydrogenation of furfural.

ACS Sustainable Chemistry & Engineering published new progress about Calcination. 97-99-4 belongs to class tetrahydrofurans, and the molecular formula is C5H10O2, Recommanded Product: (Tetrahydrofuran-2-yl)methanol.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Adeline, Naomi Joan Faray; Geue, Claudia; Hermami, Mohsen Rezaei published the artcile< Cost-effectiveness of treating hepatitis C in Seychelles.>, Application of C9H13N2O9P, the main research area is Hepatitis C; cost-effectiveness; direct-acting antiviral.

INTRODUCTION: approximately eighty million people around the world are living with hepatitis C, and 700,000 people die every year, due to hepatitis C related complications. In Seychelles, a total of 777 cases of hepatitis C were reported from 2002 to 2016, but up to mid of 2016, the cases were not being treated. Treatment with Harvoni, a combination of sofosbuvir and ledipasvir (SOF/LDV), is now being offered on the condition that the patient does not, or has stopped, injecting drugs. This paper is the first to establish the cost effectiveness of treating all cases of hepatitis C in Seychelles with Harvoni, as compared to no treatment. METHODS: data extracted from literature was used to populate an economic model to calculate cost-effectiveness from Seychelles’ government perspective. The model structure was also informed by the systematic review and an accompanying grading of economic models using the Consolidated Health Economic Evaluation Reporting Standard (CHEERS) checklist. A Markov model was developed, employing a lifetime horizon and costs and benefits were analysed from a payer’s perspective and combined into incremental cost effectiveness ratios (ICERs). RESULTS: the direct-acting antiviral (DAA), Harvoni, was found to be cost-saving in Seychelles hepatitis C virus (HCV) cohort, as compared to no treatment, with an ICER of € 753.65/QALY. The treatment was also cost-saving when stratified by gender, with the ICER of male and female being € 783.74/QALY and € 635.20/QALY, respectively. Moreover, the results obtained from acceptability curves showed that treating patients with Harvoni is the most cost-effective option, even for low thresholds. CONCLUSION: treating hepatitis C cases in Seychelles is cost-saving. It is worth developing a treatment programme to include all cases of hepatitis C, regardless of status of drug injection.

The Pan African medical journal published new progress about 58-97-9. 58-97-9 belongs to class tetrahydrofurans, and the molecular formula is C9H13N2O9P, Application of C9H13N2O9P.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Mironenko, R. M.; Belskaya, O. B.; Likholobov, V. A. published the artcile< Carbon Black as a Support in Palladium Catalysts for Hydrogenation of Organic Compounds>, Application In Synthesis of 97-99-4, the main research area is palladium carbon black catalyst hydrogenation.

The possibility of using carbon black (CB) as a support of palladium catalysts for the selective hydrogenation of organic compounds is considered. The advantages of Pd/CB catalysts are demonstrated by examples of liquid-phase hydrogenation of aromatic aldehydes and nitro compounds The combination of high catalytic parameters (activity, selectivity, and stability) achieved by these catalysts in hydrogenation reactions indicates that they are promising for use on an industrial scale, in particular in the syntheses of fine chems.

Solid Fuel Chemistry published new progress about Aldehydes Role: NUU (Other Use, Unclassified), USES (Uses). 97-99-4 belongs to class tetrahydrofurans, and the molecular formula is C5H10O2, Application In Synthesis of 97-99-4.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Salnikova, Ksenia E.; Larichev, Yurii V.; Sulman, Esther M.; Bykov, Alexey V.; Sidorov, Alexander I.; Demidenko, Galina N.; Sulman, Mikhail G.; Bronstein, Lyudmila M.; Matveeva, Valentina G. published the artcile< Selective Hydrogenation of Biomass-Derived Furfural: Enhanced Catalytic Performance of Pd-Cu Alloy Nanoparticles in Porous Polymer>, Application of C5H10O2, the main research area is biomass derived furfural hydrogenation palladium copper nanoparticle polymer catalyst; Pd−Cu alloys; furfural; hydrogenation; hypercrosslinked polystyrene; nanostructures.

Here, the development of a new catalyst is reported for the selective furfural (FF) hydrogenation to furfuryl alc. (FA) based on about 7 nm sized Pd-Cu alloy nanoparticles (NPs) formed in inexpensive, com. available micro/mesoporous hypercrosslinked polystyrene (HPS). A comparison of the catalytic properties of as-synthesized and reduced (denoted “”r””) catalysts as well as Pd-Cu alloy and monometallic palladium NPs showed a considerable enhancement of the catalytic performance of Pd-Cu/HPS-r compared to other catalysts studied, resulting in about 100% FF conversion, 95.2% selectivity for FA and a TOF of 1209 h-1. This was attributed to the enrichment of the NP surface with copper atoms, disrupting the furan ring adsorption, and to the presence of both zerovalent and cationic palladium and copper species, resulting in optimal hydrogen and FF adsorption. These factors along with exceptional stability of the catalyst in ten consecutive catalytic cycles make it highly promising in practical applications.

ChemPlusChem published new progress about Adsorption. 97-99-4 belongs to class tetrahydrofurans, and the molecular formula is C5H10O2, Application of C5H10O2.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Nazarski, Ryszard; Skolimowski, Janusz; Skowronski, Romuald published the artcile< Sterically crowded five-membered heterocyclic systems. Part I. Synthesis of acetylene derivatives of azolidyne and oxolane>, Product Details of C8H14O2, the main research area is ethynylation Favorskii pyrrolidinone tetramethyl; alkynylation tetrahydrofuranone tetramethyl; alkynylpyrrolidinol tetramethyl; alkynylfuranol tetrahydrotetramethyl.

Alkynyl 5-membered heterocyclic compounds I (R = H, Ph; X = O, NH) were prepared by alkynylation of the heterocyclic ketones II by the Favorskii alkynylation (KOH, alkyne, THF) or Grignard-Iotsitch method (EtMgBr, alkyne). Favorskii ethynylation of II (X = NH) gave 44% I (R = H; X = NH), whereas Favorskii ethynylation of II (X = O) gave no ethynylation product which indicated that the amino group in II (X = NH) acts as a catalyst in the ethynylation.

Polish Journal of Chemistry published new progress about 5455-94-7. 5455-94-7 belongs to class tetrahydrofurans, and the molecular formula is C8H14O2, Product Details of C8H14O2.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Mineguchi, Yuri; Goto, Kyosuke; Sudo, Yuna; Hirayama, Kentaro; Kashiwagi, Hirotoshi; Sasagase, Izumi; Kitazawa, Haruki; Asakuma, Sadaki; Fukuda, Kenji; Urashima, Tadasu published the artcile< Characterisation of sugar nucleotides in colostrum of dairy domestic farms animals>, Recommanded Product: ((2R,3S,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate, the main research area is colostrum sugar nucleotide UMP UDP.

The biol. significance and heterogeneity of bovine, caprine and ovine colostrum sugar nucleotides is unclear. Colostrum sugar nucleotides and sugar monophosphates were purified and characterised with 1H-NMR spectroscopy. UDP-galactose (UDP-Gal) and UDP-glucose (UDP-Glc) were identified in colostrum of Holstein and Brown Swiss cows; UDP-Gal, UDP-Glc, UDP-N-acetylgalactosamine (UDP-GalNAc) and UDP-N-acetylglucosamine (UDP-GlcNAc) were found in Japanese Saanen goat colostrum. UDP-Gal, UDP-Glc, UDP-GalNAc and UDP-GlcNAc were found in Corriedale sheep but not in the Suffolk and Fraise Land breeds. The presence/absence of these sugar nucleotides in colostrum is heterogeneous among dairy domestic farm animals and the three sheep breeds. In addition, a nucleotide, uridine-ribose diphosphate (UDP) was identified in the colostra of Japanese Saanen goat, and Suffolk and Fraiseland sheep, while uridine-ribose monophosphate (UMP) was detected in the colostrum of Brown Swiss cow and the three breed sheep. N-acetylglucosamine-1-phosphate (GlcNAc-1-P) was also identified in the colostrum of the goat and two cow breeds.

International Dairy Journal published new progress about Bos taurus. 58-97-9 belongs to class tetrahydrofurans, and the molecular formula is C9H13N2O9P, Recommanded Product: ((2R,3S,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Phanthuwongpakdee, Jakkapon; Harimoto, Toyohiro; Babel, Sandhya; Dwivedi, Sumant; Takada, Kenji; Kaneko, Tatsuo published the artcile< Flame retardant transparent films of thermostable biopolyimide metal hybrids>, Electric Literature of 4415-87-6, the main research area is flame retardant transparent film thermostable bio polyimide metal hybrid.

The development of flame retardant transparent films is important for elec. devices and building materials it but it is still a challenge. Herein, flame retardant films having high optical transparency were developed from the amino acid-based biopolyimide (BPI) salt with aluminum (BPI-COOAl) and copper ions (BPI-COOCu). The microscale combustion calorimetry anal. revealed that for BPI-COOAl, the total heat released (THR) and peak heat released rate were 4.5 W/g and 18.9 kJ/g, resp. These values were lower than those of its precursors and BPI-COOCu. BPI-COOAl was rated V-0 for the Underwriters Laboratories vertical burning standard test. The polymer also retained a high transparency of more than 80% transmittance at a wavelength of 450 nm. The tensile strength was also preserved at 63.7 MPa. For BPI-COOCu, 14.6 kJ/g THR and 47.1 MPa tensile strength were observed When a colorful ion such as Cu was used, BPI-COOCu became a flame retardant film that was a green filter. The char formation of Al2O3 and Cu2O in their resp. polymer complexes was deduced as the main flame suppression mechanism. The present films of biopolyimide salts are advantageous in showcasing the balance of different essential material properties such as flame retardancy, thermo-mech. stability, and transparency.

Polymer Degradation and Stability published new progress about Cation exchange. 4415-87-6 belongs to class tetrahydrofurans, and the molecular formula is C8H4O6, Electric Literature of 4415-87-6.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Morgado-Carrasco, Daniel; Combalia, Andrea; Fustà-Novell, Xavier; Mascaró, José Manuel Jr; Iranzo, Pilar published the artcile< Aggressive erosive lichen planus associated with hepatitis C responding to sofosbuvir/ledipasvir treatment.>, Synthetic Route of 58-97-9, the main research area is .

There is no abstract available for this document.

Indian journal of dermatology, venereology and leprology published new progress about 58-97-9. 58-97-9 belongs to class tetrahydrofurans, and the molecular formula is C9H13N2O9P, Synthetic Route of 58-97-9.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Popov, Yu. V.; Mokhov, V. M.; Nebykov, D. N.; Shirkhanyan, P. M.; Gendler, T. A.; Shemet, V. V. published the artcile< Colloidal and Nanosized Catalysts in Organic Synthesis: XXIV. Study of Hydrogenation of Furan and Its Derivatives in the Presence of MgO-Supported Nickel and Cobalt Nanoparticles>, Category: tetrahydrofurans, the main research area is furan hydrogenation nickel nanocatalyst plug flow reactor.

The processes of hydrogenation of furan and its derivatives (2-methylfuran, furfuryl alc., and furfural) in plug-flow type reactor under atm. hydrogen pressure at 20-220°C in the presence of supported nickel nanoparticles prepared via chem. reduction have been investigated. It has been found that nickel nanoparticles supported on magnesium oxide surface are the most reactive and stable under the considered conditions. This catalyst allows the corresponding hydrogenation products with 100% yield and complete conversion of the substrate.

Russian Journal of General Chemistry published new progress about Furans Role: RCT (Reactant), RACT (Reactant or Reagent). 97-99-4 belongs to class tetrahydrofurans, and the molecular formula is C5H10O2, Category: tetrahydrofurans.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Byun, Mi Yeon; Lee, Man Sig published the artcile< Pt supported on hierarchical porous carbon for furfural hydrogenation>, HPLC of Formula: 97-99-4, the main research area is furfural hydrogenation hierarchical porous carbon platinum catalyst.

Hierarchical porous carbon (HPC) was prepared using colloidal silica of different sizes as a template, and used as a support for Pt nanoparticles. The Pt dispersion varied with the pore size and structure of the HPC supports. However, the measured Pt dispersions (70%-76%) suggested that this characteristic was not affected by the pore size distribution above a certain size. The activities of the prepared Pt/HPC catalysts for furfural hydrogenation were then investigated. The HPC supports with large pores allowed for greater contact between the Pt nanoparticles and reactants due to the high mass transfer rate, resulting in the highest furfural conversion and 1-pentanol selectivity. In contrast, the HPC supports with small pores exhibited higher furfuryl alc. selectivities. The effect of the solvent on furfural hydrogenation was also investigated, and it was found that the solubility of H2 in the solvent affected the furfural conversion and product selectivity.

Journal of Industrial and Engineering Chemistry (Amsterdam, Netherlands) published new progress about Catalyst supports. 97-99-4 belongs to class tetrahydrofurans, and the molecular formula is C5H10O2, HPLC of Formula: 97-99-4.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem