Category: Tetrahydrofurans

Takada, Kenji; Shinagawa, Hiromasa; Morita, Yuki; Grewal, Manjit S.; Taya, Kazuya; Kumar, Amit; Kaneko, Tatsuo published the artcile< Syntheses of Soluble Biopolyimides Using 4-Aminophenylalanine>, Electric Literature of 4415-87-6, the main research area is aminophenylalanine tetracarboxylic dianhydride polyamic acid thermal imidization biopolyimide.

4-Aminophenylalanine (4APhe), an exotic amino acid which is obtained as a microorganism metabolite of glucose, is polycondensed with various tetracarboxylic dianhydrides as a diamine monomer to obtain poly(amic acid)s. Subsequent thermal imidization of poly(amic acid)s is made at 220°C with stepwise heating from 100°C. Some of the obtained polyimides (PIs) exhibited good solubility in organic solvents such as N,N-dimethylformamide, N,N-dimethylacetamide, and more. The progress of imidization was observed by proton NMR and IR spectroscopy to confirm that the imidization ratio was up to 98%. Carboxylate group of the side-chains of PIs affected their solubilities despite the high imidization ratio, and the solubility was lost for any organic solvents by decarboxylation at 280°C, confirmed from mass-loss of thermogravimetric anal. Thus, a new series of PIs were obtained with abilities of solvent-molding in PI state and thermal resistivity enhancement by further heating after molding.

Chinese Journal of Polymer Science published new progress about Glass transition temperature. 4415-87-6 belongs to class tetrahydrofurans, and the molecular formula is C8H4O6, Electric Literature of 4415-87-6.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Guerra Romero, Adriana R; Pérez Figueras, Manuel; Alonso López, Sonia published the artcile< Successful evolution of morphea after hepatitis C virus eradication with direct-acting antiviral agent treatment.>, Category: tetrahydrofurans, the main research area is .

Hepatitis C virus infection has been associated with many dermatologic conditions such as lichen planus, porphyria cutanea tarda, and cryoglobulinemia. Recently, an association of HCV with systemic sclerosis has been reported. However, there are few reports of the association of localized scleroderma or morphea with Hepatitis C Virus infection. We describe the case of a 36 years old female patient suffering from prolonged morphea with difficult management, who was recently diagnosed of Hepatitis C Virus and received direct-acting antiviral agents treatment with Hepatitis C Virus clearance. Skin lesion faded away in a short period after successful therapy.

Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva published new progress about 58-97-9. 58-97-9 belongs to class tetrahydrofurans, and the molecular formula is C9H13N2O9P, Category: tetrahydrofurans.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Shibutani, Shotaro; Kodo, Taiga; Takeda, Mitsutaka; Nagao, Kazunori; Tokunaga, Norihito; Sasaki, Yusuke; Ohmiya, Hirohisa published the artcile< Organophotoredox-Catalyzed Decarboxylative C(sp3)-O Bond Formation>, Electric Literature of 97-99-4, the main research area is ether secondary amine thioether preparation; alc amine thiol dioxoisoindolinyl carboxylate photoredox decarboxylative coupling.

This manuscript reports a visible-light-mediated organosulfide catalysis that enables the decarboxylative coupling between simple aliphatic alc. and tertiary or secondary alkyl carboxylic acid-derived redox active esters to produce a C(sp3)-O-C(sp3) fragment. Results of the coupling using other heteroatom nucleophiles such as water, amides, and thiols are also described.

Journal of the American Chemical Society published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 97-99-4 belongs to class tetrahydrofurans, and the molecular formula is C5H10O2, Electric Literature of 97-99-4.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Hagens, Graham; Wasacz, John P.; Joullie, Madeleine; Yates, Peter published the artcile< Photolysis of 2,2,5,5-tetramethyldihydro-3-furanone>, SDS of cas: 5455-94-7, the main research area is furanones photolysis; photolysis furanones.

The photolysis of 2,2,5,5-tetramethyldihydro-3(2H)-furanone in MeOH gives Me 3-isopropoxy-3-methylbutanoate, Me 3-methyl-2-butenoate, iso-Pr 3-methyl-2-butenoate, Me 3-methyl-3-butenoate, and iso-PrOH. These products are all considered to arise via the ketene formed by Norrish type I cleavage of the dihydrofuranone followed by intramol. H abstraction. Corroboration for this view is that photolysis of 2,2,5,5-tetramethyldihydro-3(2H)-furanone-4-d2 in MeOH gives Me 3-(isopropoxy-2-d)-3-methylbutanoate and Me 3-methyl-2-butenoate-2-d.

Journal of Organic Chemistry published new progress about Photolysis. 5455-94-7 belongs to class tetrahydrofurans, and the molecular formula is C8H14O2, SDS of cas: 5455-94-7.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Wanderley, Ricardo R.; Pinto, Diego D. D.; Knuutila, Hanna K. published the artcile< Investigating opportunities for water-lean solvents in CO2 capture: VLE and heat of absorption in water-lean solvents containing MEA>, COA of Formula: C5H10O2, the main research area is flue gas carbon dioxide absorption water lean solvent; amine wet scrubbing carbon dioxide absorption; vapor liquid equilibrium water lean solvent carbon dioxide absorption; high volatility solvent carbon dioxide absorption; low volatility solvent carbon dioxide absorption.

A thorough study of a set of organic diluents for water-lean solvent formulation was conducted. Performance of 30 weight percent/weight aqueous monoethanolamine (MEA) 30 was compared to that of mixtures of 30 weight percent/weight MEA and methanol, acetone, monoethylene glycol (MEG), N-methyl-2-pyrrolidone (NMP), tetrahydrofurfuryl alc. (THFA), sulfolane, cyclopentanone (CC5), furfuryl alc., and γ-butyrolactone. A small calorimeter was used to obtain vapor-liquid equilibrium (VLE) and heat of absorption data. Shifting from aqueous to non-aqueous solvents had significant implications for VLE, since all water-lean solvents had lower CO2 solubility than aqueous MEA; however, heat of absorption was not much affected. Results showed the limitations of using most ethers, esters, and ketones for water-lean solvent formulation, all stemming from the very low dielec. permittivity of these diluents and the difficulty of stabilizing intermediate reaction species between MEA and CO2 within these systems. Nevertheless, the low volatility of solvents containing MEG, NMP, or THFA could offer opportunities for processes with overall less reboiler heat duties than that of ordinary aqueous MEA.

Separation and Purification Technology published new progress about Absorption. 97-99-4 belongs to class tetrahydrofurans, and the molecular formula is C5H10O2, COA of Formula: C5H10O2.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Wu, Jingcheng; Zhang, Xinghua; Chen, Qiang; Chen, Lungang; Liu, Qiying; Wang, Chenguang; Ma, Longlong published the artcile< One-Pot Hydrogenation of Furfural into Tetrahydrofurfuryl Alcohol under Ambient Conditions over PtNi Alloy Catalyst>, Product Details of C5H10O2, the main research area is furfural one pot hydrogenation tetrahydrofurfuryl alc platinum nickel alloy.

Furfural (FAL), a promising renewable platform compound from biomass, can be totally hydrogenated to an industrially important platform chem., tetrahydrofurfuryl alc. (THFA). In this work, a high yield of THFA was obtained by one-pot hydrogenation of FAL over a PtNi catalyst under mild reaction conditions. Small PtNi alloy particles were well distributed on active carbon. The catalysts were characterized by several phys.-chem. technologies (transmission electron microscopy, X-ray diffraction, energy-dispersive spectroscopy, and inductively coupled plasma spectroscopy). Temperature-programmed reduction with hydrogen and in situ XPS demonstrate the presence of PtNi alloy. The electron-rich metal Pt could facilitate the heterolytic dissociation of hydrogen and promote the hydrogenation of FAL. Pt sites on the surface facilitate the adsorption at aldehyde (C=O) groups, and the furan ring strongly adsorbs on the Ni surface. Low reaction temperature is advantageous to reduce side reactions. Various metal concentrations were employed in this reaction; Pt(3)Ni(3)/C catalyst exhibits the best performance, achieving 99% FAL conversion and 93% THFA yield at 35°C and under 2 MPa H2.

Energy & Fuels published new progress about Hydrogenation catalysts. 97-99-4 belongs to class tetrahydrofurans, and the molecular formula is C5H10O2, Product Details of C5H10O2.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Dwivedi, Sumant; Nag, Aniruddha; Sakamoto, Shigeki; Funahashi, Yasuyoshi; Harimoto, Toyohiro; Takada, Kenji; Kaneko, Tatsuo published the artcile< High-temperature resistant water-soluble polymers derived from exotic amino acids>, Reference of 4415-87-6, the main research area is temperature resistant water soluble polyimide preparation.

High-performance water-soluble polymers have a wide range of applications from engineering materials to biomedical plastics. However, existing materials are either natural polymers that lack high thermostability or rigid synthetic polymers. Therefore, we design an amino acid-derived building block, 4,4′-diamino-α-truxillate dianion (4ATA2-), that induces water solubility in high-performance polymers. Polyimides containing 4ATA2- units are intrinsically water-soluble and are processed into films cast from an aqueous solution The resulting polyimide films exhibit exceptional transparency and extremely high thermal stability. In addition, the films can be made insoluble in water by simple post-treatment using weak acid or multivalent metal ions such as calcium. The synthesized polyimide’s derived from bio-based resources are useful for yielding waterborne polymeric high-performance applications.

RSC Advances published new progress about Elongation at break. 4415-87-6 belongs to class tetrahydrofurans, and the molecular formula is C8H4O6, Reference of 4415-87-6.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Tal, Nitzan; Morehouse, Benjamin R.; Millman, Adi; Stokar-Avihail, Avigail; Avraham, Carmel; Fedorenko, Taya; Yirmiya, Erez; Herbst, Ehud; Brandis, Alexander; Mehlman, Tevie; Oppenheimer-Shaanan, Yaara; Keszei, Alexander F. A.; Shao, Sichen; Amitai, Gil; Kranzusch, Philip J.; Sorek, Rotem published the artcile< Cyclic CMP and cyclic UMP mediate bacterial immunity against phages>, Recommanded Product: ((2R,3S,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate, the main research area is Pycsar; anti-phage; bacteria; cCMP; cUMP; cyclase; defense; pb8; phage; pyrimidine.

The cyclic pyrimidines 3′,5′-cyclic cytidine monophosphate (cCMP) and 3′,5′-cyclic uridine monophosphate (cUMP) have been reported in multiple organisms and cell types. As opposed to the cyclic nucleotides 3′,5′-cyclic adenosine monophosphate (cAMP) and 3′,5′-cyclic guanosine monophosphate (cGMP), which are second messenger mols. with well-established regulatory roles across all domains of life, the biol. role of cyclic pyrimidines has remained unclear. Here we report that cCMP and cUMP are second messengers functioning in bacterial immunity against viruses. We discovered a family of bacterial pyrimidine cyclase enzymes that specifically synthesize cCMP and cUMP following phage infection and demonstrate that these mols. activate immune effectors that execute an antiviral response. A crystal structure of a uridylate cyclase enzyme from this family explains the mol. mechanism of selectivity for pyrimidines as cyclization substrates. Defense systems encoding pyrimidine cyclases, denoted here Pycsar (pyrimidine cyclase system for antiphage resistance), are widespread in prokaryotes. Our results assign clear biol. function to cCMP and cUMP as immunity signaling mols. in bacteria.

Cell (Cambridge, MA, United States) published new progress about 58-97-9. 58-97-9 belongs to class tetrahydrofurans, and the molecular formula is C9H13N2O9P, Recommanded Product: ((2R,3S,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Peijnenburg, W. J. G. M.; Buck, H. M. published the artcile< The effects of substituents and solvent polarity on photochemical [1,3] sigmatropic shifts. Experimental evidence in favor of the occurrence of sudden polarization in acyclic alkenes>, Name: 2,2,5,5-Tetramethyldihydrofuran-3(2H)-one, the main research area is photorearrangement ethylidenenaphthalenol mechanism.

On direct irradiation of I in various solvents, fast E-Z isomerization around the exocyclic double bond was observed This led to the formation of a 50:50 mixture of E/Z isomers. Further irradiation of this mixture resulted in the clean formation of II, the product derived from a photochem. [1,3]-OH shift in I or its geometric isomer. The yield of II decreases going from a highly apolar solvent to the most polar solvent, n-hexane-autonitrile. This result is a clear support in favor of the sudden polarization mode 1.

Tetrahedron published new progress about Photorearrangement. 5455-94-7 belongs to class tetrahydrofurans, and the molecular formula is C8H14O2, Name: 2,2,5,5-Tetramethyldihydrofuran-3(2H)-one.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Luo, Yang; Ma, Hong; Zhang, Shujing; Zheng, Daoyuan; Che, Penghua; Liu, Xin; Zhang, Meiyun; Gao, Jin; Xu, Jie published the artcile< Binding Energy as Driving Force for Controllable Reconstruction of Hydrogen Bonds with Molecular Scissors>, Application of C5H10O2, the main research area is binding energy hydrogen bond mol scissor.

Hydrogen bonds are one of the most important directional intermol. interactions and play key roles in chem. and biochem. systems, but there is still a lack of prediction and understanding of their control. Herein, hydrogen-binding energy (EHB) acted as a driving force for controllably reconstructing hydrogen bonds with mol. scissors. We related hydrogen-binding energies of the donor-acceptor couple (EHB,2) and the donor itself (EHB,1) and ΔG based on ΔG = a1EHB,1 + a2EHB,2 + a3. When EHB,1 and EHB,2 satisfy the condition ΔG < 0, the acceptor is predicted as mol. scissors with sufficient reconstruction capacity in breaking the initial hydrogen bonds and forming new ones. Remarkably, we developed an exptl. method to determine the EHB values by a linear equation as a function of chem. shifts (δ), which is innovational since in the former research EHB can only be deduced from empirical formulas and DFT calculation On that basis, the hydrogen bonds of α-cellulose were broken and re-formed in mol. scissors-consisting deep eutectic solvents, leading to the white powder transforming into a hydrogel and colorless and transparent thin film materials with distinct crystalline structure, surface flatness, and morphol. Journal of the American Chemical Society published new progress about Binding energy. 97-99-4 belongs to class tetrahydrofurans, and the molecular formula is C5H10O2, Application of C5H10O2.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem