Category: Tetrahydrofurans

Nikul’shin, P A’s team published research in Chemistry and Technology of Fuels and Oils in 2020-01-31 | 97-99-4

Chemistry and Technology of Fuels and Oils published new progress about Biomass hydrotreatment. 97-99-4 belongs to class tetrahydrofurans, and the molecular formula is C5H10O2, Formula: C5H10O2.

Nikul’shin, P. A.; Ershov, M. A.; Grigor’yeva, E. V.; Tarazanov, S. V.; Kuznetsova, S. N.; Repina, O. V. published the artcile< Furfural Derivatives as Fuel Components>, Formula: C5H10O2, the main research area is furfural derivative fuel component additive.

Furfural derivatives prepared from vegetable raw materials have recently become popular as high-performance fuel additives. Furfural oxygenates are particularly of interest. A lot of research was devoted to preparing new materials from furfural, however, there is much to be discovered about their effect on physicochem. properties of fuels. The possibility of using furfural derivatives, obtained by their hydrogenation on copper and nickel catalysts with full conversion of furfural, as additives to fuel is considered in this article. Their impact on antiknock properties and chem. stability is evaluated. Futons are mostly effective in low-octane hydrocarbon bases, such as hydrocracking gasoline, at a concentration of 5-30 weight %. A high concentration of potential resins can lead to the formation of deposits in the combustion chamber of the engine, which, in turn, requires addnl. research.

Chemistry and Technology of Fuels and Oils published new progress about Biomass hydrotreatment. 97-99-4 belongs to class tetrahydrofurans, and the molecular formula is C5H10O2, Formula: C5H10O2.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Vega, Ana D’s team published research in Antiviral Therapy in 2019 | 58-97-9

Antiviral Therapy published new progress about Antiviral agents. 58-97-9 belongs to class tetrahydrofurans, and the molecular formula is C9H13N2O9P, Application In Synthesis of 58-97-9.

Vega, Ana D.; Hynicka, Lauren M.; Claeys, Kimberly; Chua, Joel V.; Heil, Emily L. published the artcile< Effectiveness of 8 weeks of ledipasvir/sofosbuvir for hepatitis C in HCV-HIV-coinfected patients>, Application In Synthesis of 58-97-9, the main research area is ledipasvir sofosbuvir antiviral agent hepatitis C virus HIV.

Background: Data is limited on the use of 8 wk of therapy with ledipasvir/sofosbuvir (LDV/SOF) for special populations such as HCV-HIV-coinfected patients. The primary objective of this anal. was to compare sustained virol. response at 12 wk after end of therapy (SVR12) rates among HCV-monoinfected and HCV-HIV-coinfected patients in a real-world clin. setting. Addnl., we compared SVR12 rates among patients receiving 8 vs. 12 wk of therapy. Methods: This was a single-center, retrospective study of HCV-infected patients prescribed LDV/SOF at ambulatory clinics associated with the University of Maryland Medical Center (UMMC) from May 2015 to May 2016. Data were obtained from UMMC electronic medical records and outpatient pharmacy claims database. Comparisons between groups were made using χ2 or Fisher’s exact test for categorical variables and Student’s t-test or Wilcoxon rank-sum for continuous variables. All analyses were per-protocol; patients missing SVR12 data (25.2%) could not be evaluated for our stated objectives. Results: A total of 274 patients were included. Median age was 58 years; 62.8% were male; 82.5% were Black. SVR12 data was available for 65 HCV-HIV-coinfected patients, of which 62 (95.4%) achieved SVR12. There was no difference in SVR12 rate between HCV-HIV-coinfected patients and HCV-monoinfected patients (86/90; 95.6%; P=0.959). Addnl., there was no difference in SVR12 attainment between HIV-HCV-coinfected patients who received 8 vs. 12 wk of therapy (P=0.101). Conclusions: 8 wk of LDV/SOF was effective for treatment-naive, non-cirrhotic, HCV genotype-1 patients in this real-world setting, regardless of HIV status. Increased uptake of the 8-wk regimen can decrease costs for patients and payers without compromising outcomes.

Antiviral Therapy published new progress about Antiviral agents. 58-97-9 belongs to class tetrahydrofurans, and the molecular formula is C9H13N2O9P, Application In Synthesis of 58-97-9.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Zhang, Jinxin’s team published research in ACS Sustainable Chemistry & Engineering in 2021-10-18 | 97-99-4

ACS Sustainable Chemistry & Engineering published new progress about Activation energy. 97-99-4 belongs to class tetrahydrofurans, and the molecular formula is C5H10O2, Recommanded Product: (Tetrahydrofuran-2-yl)methanol.

Zhang, Jinxin; Mao, Donglei; Wu, Dongfang published the artcile< Industrially Applicable Aqueous-Phase Selective Hydrogenation of Furfural on an Efficient TiOx-Modified Ni Nanocatalyst>, Recommanded Product: (Tetrahydrofuran-2-yl)methanol, the main research area is industrially aqueous phase selective hydrogenation furfural titania nickel nanocatalyst.

Because water is involved in the formation of furfural (FFR), aqueous-phase selective hydrogenation of FFR to furfuryl alc. (FOL) has the potential for industrial applications, but it has not yet been well exploited. Here, partially reduced TiOx-modified Ni nanocatalysts were studied. The Ni-TiO2 interaction adjusts the Ni electron structure and affects the catalyst adsorption properties. FFR is adsorbed on the TiOx oxygen vacancy (OV) by C=O, and the FOL selectivity is pos. correlated with the surface OV content. The active H atoms dissociated on Ni spillover to the TiOx surface and then attack the adsorbed FFR C=O. The precise synergistic effect of Ni and OV improves the comprehensive performance of FFR hydrogenation. Under mild conditions, FFR conversion can reach 92.5% and FOL selectivity can be as high as 96.8%. This is an extremely excellent performance of aqueous-phase FFR selective hydrogenation, and thus, the TiOx-modified Ni nanocatalyst is a very promising candidate for industrial applications.

ACS Sustainable Chemistry & Engineering published new progress about Activation energy. 97-99-4 belongs to class tetrahydrofurans, and the molecular formula is C5H10O2, Recommanded Product: (Tetrahydrofuran-2-yl)methanol.

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Kang, Wenyue’s team published research in Catalysts in 2020 | CAS: 19444-84-9

3-Hydroxydihydrofuran-2(3H)-one(cas: 19444-84-9) is a 5-membered cyclic ester. It was obtained via tin-conversion of biomass-derived 1,3-dihydroxyacetone (DHA) and formaldehyde. And it may be employed as starting reagent in the synthesis of series of seco-pseudonucleoside synthons via aminolysis.Application of 19444-84-9

The author of 《Selective production of acetic acid via catalytic fast pyrolysis of hexoses over potassium salts》 were Kang, Wenyue; Zhang, Zhijun. And the article was published in Catalysts in 2020. Application of 19444-84-9 The author mentioned the following in the article:

Glucose and fructose are widely available and renewable resources. They were used to prepare acetic acid (AA) under the catalysis of potassium acetate (KAc) by thermogravimetric anal. and pyrolysis coupled with gas chromatog. and mass spectrometry. The TGA result showed that the KAc addition lowered the glucose’s thermal decomposition temperatures (about 30°C for initial decomposition temperature and 40°C for maximum mass loss rate temperature), implying its promotion of glucose’s decomposition The Py-GC/MS tests illustrated that the KAc addition significantly altered the composition and distribution of hexose pyrolysis products. The maximum yield of AA was 52.1% for the in situ catalytic pyrolysis of glucose/KAc (1:0.25 wt/wt) mixtures at 350°C for 30 s. Under the same conditions, the AA yield obtained from fructose was 48% and it increased with the increasing amount of KAc. When the ratio reached to 1:1, the yield was 53.6%. In comparison, a study of in situ and online catalytic methods showed that KAc can not only catalyze the primary cracking of glucose, but also catalyze the cracking of a secondary pyrolysis stream. KAc plays roles in both phys. heat transfer and chem. catalysis. The experimental process involved the reaction of 3-Hydroxydihydrofuran-2(3H)-one(cas: 19444-84-9Application of 19444-84-9)

3-Hydroxydihydrofuran-2(3H)-one(cas: 19444-84-9) is a 5-membered cyclic ester. It was obtained via tin-conversion of biomass-derived 1,3-dihydroxyacetone (DHA) and formaldehyde. And it may be employed as starting reagent in the synthesis of series of seco-pseudonucleoside synthons via aminolysis.Application of 19444-84-9

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Wang, Peng’s team published research in ChemPlusChem in 2020 | CAS: 696-59-3

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.HPLC of Formula: 696-59-3

HPLC of Formula: 696-59-3In 2020 ,《A Reductive Supramolecular Hydrogel: A Platform for Facile Fabrication of Diverse Metal-Nanoparticle-Decorated Conductive Networks with Spatiotemporal Control》 appeared in ChemPlusChem. The author of the article were Wang, Peng; He, Guokang; Ji, Jingwei; Li, Jian; Zhou, Kang; Tian, Li; Feng, Kai; Sun, Fuwei; Li, Guangtao. The article conveys some information:

Nanoparticle-hydrogel hybrid composites have a great potential for a broad range of applications, such as antibacterial materials, stimuli-responsive materials and catalysis. A novel supramol. hydrogel system was developed using an amino acid based amphiphile containing a terminal pyrrole moiety as a gelator. The pyrrole moiety could serve as both reducing agent and monomer, and a variety of metal precursors penetrating into the hydrogel could be reduced in situ into metal nanoparticles while the pyrrole moieties preorganized in hydrogel were oxidized into polyprroles, affording metal-nanoparticle-decorated covalent conductive networks. This strategy allows the facile fabrication of diverse mono- or multimetallic nanoparticle-polymer networks from one hydrogel by a simple reaction-diffusion approach. More importantly, besides homogeneous composites, unique multisegment heterogeneous systems with spatiotemporal control were also easily accessible. Furthermore, based on the same multifunctional mol., the fabrication of hierarchically pore-structured metal-nanoparticles-polymers as well as metal-nanoparticles-carbon structures was also realized. In addition to this study using 2,5-Dimethoxytetrahydrofuran, there are many other studies that have used 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3HPLC of Formula: 696-59-3) was used in this study.

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.HPLC of Formula: 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Li, Ziting’s team published research in ChemNanoMat in 2022 | CAS: 696-59-3

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Electric Literature of C6H12O3

Li, Ziting; Cui, Shisheng; Yu, Jiayu; Qu, Jiamin; Shi, Jianbing; Tong, Bin; Cai, Zhengxu; Dong, Yuping published an article in 2022. The article was titled 《Amphiphilic and Zwitterionic Multi Arylpyrroles with Near-Infrared Aggregation-Induced Emission for Cell Membrane Imaging》, and you may find the article in ChemNanoMat.Electric Literature of C6H12O3 The information in the text is summarized as follows:

The cell membrane protects the cell stability and balance and participates in various physiol. activities as an exchange channel. Therefore, the real-time monitoring of cell membrane biol. dynamics can help us understand the physiol. state of the current cell. Herein, a type of amphiphilic near IR (NIR) aggregation-induced emission (AIE) mols. was designed and synthesized. Multiarylpyrroles (MAPs) with a dodecyl chain at the 1-position of the pyrrole ring, charged pyridinium sulfonate at the 2,5-position of the pyrrole ring and free rotating aryls at the 3-position of the pyrrole ring can target cell membranes. One of the MAPs, MAP22, had a maximum emission wavelength in the aggregation state of up to 721 nm with a large Stokes shift (∼280 nm). In addition, MAP22 nanoparticles can produce reactive oxygen species (ROS) with a quantum yield of 224%. Therefore, these AIE MAPs are promising candidates for theranostic nanoagents, including NIR fluorescence imaging to target cell membranes and ablate cancer cells by producing ROS. After reading the article, we found that the author used 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Electric Literature of C6H12O3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Electric Literature of C6H12O3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Xin, Xing’s team published research in Food Control in 2021 | CAS: 696-59-3

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Reference of 2,5-Dimethoxytetrahydrofuran

Xin, Xing; Bissett, Amy; Wang, Joyce; Gan, Andrew; Dell, Kiri; Baroutian, Saeid published an article in 2021. The article was titled 《Production of liquid smoke using fluidised-bed fast pyrolysis and its application to green lipped mussel meat》, and you may find the article in Food Control.Reference of 2,5-Dimethoxytetrahydrofuran The information in the text is summarized as follows:

Liquid smoke flavouring as an all-natural food additive is usually prepared by smoldering or a carbonisation method. In this study, liquid smoke was prepared by fast pyrolysis technol. using a fluidised bed reactor with a yield of 30 wt%. GC-MS anal. showed that main functional compounds were furans, carbonyls and phenols. The fast pyrolysis liquid smoke presented a high antioxidant capacity with a total phenolic content of 21.9 mg GAE/mL. Cytotoxicity anal. indicated that it was as safe as com. liquid smoke products. This fast pyrolysis liquid smoke was diluted and applied to treat green lipped mussel meat, and the preserving effects were studied over 30-day refrigerated storage. The microbiol. anal. results showed bacteria growth was inhibited during the first 14 days of the storage period. The image and texture anal. results showed insignificant changes to liquid smoked mussel meat during storage except for color darkening and decreased hardness in meat texture. After reading the article, we found that the author used 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Reference of 2,5-Dimethoxytetrahydrofuran)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Reference of 2,5-Dimethoxytetrahydrofuran

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Guillon, Jean’s team published research in Molbank in 2020 | CAS: 696-59-3

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Synthetic Route of C6H12O3

Synthetic Route of C6H12O3In 2020 ,《1-phenyl-8-[[4-(pyrrolo[1,2-a]quinoxalin-4-yl)phenyl]methyl]-1,3,8-triazaspiro[4.5]decan-4-one: synthesis, crystal structure and anti-leukemic activity》 appeared in Molbank. The author of the article were Guillon, Jean; Savrimoutou, Solene; Rubio, Sandra; Moreau, Stephane; Pinaud, Noel; Marchivie, Mathieu; Desplat, Vanessa. The article conveys some information:

A multi-step synthesis of 1-phenyl-8-[[4-(pyrrolo[1,2-a]quinoxalin-4-yl)phenyl]methyl]-1,3,8-triazaspiro[4.5]decan4-one using 2-nitroaniline as starting material was reported. Structure characterization of this original pyrrolo[1,2-a]quinoxaline derivative was achieved by FT-IR, 1H-NMR, 13C-NMR, X-Ray and HRMS spectral anal. This title compound showed interesting cytotoxic potential against several human leukemia cell lines (K562, HL60, and U937 cells). The experimental process involved the reaction of 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Synthetic Route of C6H12O3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Synthetic Route of C6H12O3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Guillon, Jean’s team published research in Molbank in 2022 | CAS: 696-59-3

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Application of 696-59-3

In 2022,Guillon, Jean; Savrimoutou, Solene; Albenque-Rubio, Sandra; Pinaud, Noel; Moreau, Stephane; Desplat, Vanessa published an article in Molbank. The title of the article was 《Synthesis, Crystal Structure and Anti-Leukemic Activity of 1,3-Dihydro-1-{1-[4-(4-phenylpyrrolo[1,2-a]quinoxalin-3-yl)benzyl]piperidin-4-yl}-2H-benzimidazol-2-one》.Application of 696-59-3 The author mentioned the following in the article:

Substituted pyrrolo[1,2-a]quinoxaline compound I was synthesized through a multi-step pathway starting from com. available 2-nitroaniline. A structure characterization of compound I was achieved by using FT-IR, 1H-NMR, 13C-NMR, X-Ray and HRMS spectral anal. This new compound I showed an interesting cytotoxic potential against several human leukemia cell lines (HL60, K562 and U937 cells).2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Application of 696-59-3) was used in this study.

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Application of 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Li, Shichen’s team published research in Synthesis in 2022 | CAS: 696-59-3

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.HPLC of Formula: 696-59-3

Li, Shichen; Lv, Xueyan; Ren, Jianing; Feng, Lei; Ma, Chen published an article in 2022. The article was titled 《A Direct Method for Synthesis of Fluorinated Quinazolinones and Quinoxalines Using Fluorinated Acids without Metals or Additives》, and you may find the article in Synthesis.HPLC of Formula: 696-59-3 The information in the text is summarized as follows:

A direct method using trifluoroacetic acid as a CF3 source for the synthesis of 2-(trifluoromethyl)quinazolin-4-ones and 4-(trifluoromethyl)pyrrolo/indolo[1,2- a]quinoxalines without any catalysts or additives was reported; a wide range of fluorinated compounds were obtained in 52%-94% yield. The results came from multiple reactions, including the reaction of 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3HPLC of Formula: 696-59-3)

2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.HPLC of Formula: 696-59-3

Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem