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Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Recommanded Product: 15833-61-1. Introducing a new discovery about 15833-61-1, Name is (Tetrahydrofuran-3-yl)methanol

Selective alkylation of a 6,7-dihydroxyquinazoline

A convenient 3-step multi-parallel process for the preparation of 4-(3-chloro-2-fluoroanilino)-6,7-bisalkoxyquinazolines is highlighted.

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Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

The Absolute Best Science Experiment for (Tetrahydrofuran-3-yl)methanol

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Difluorocyclobutylacetylenes as positive allosteric modulators of mGluR5 with reduced bioactivation potential

Schizophrenia is a serious illness that affects millions of patients and has been associated with N-methyl-D-aspartate receptor (NMDAR) hypofunction. It has been demonstrated that activation of metabotropic glutamate receptor 5 (mGluR5) enhances NMDA receptor function, suggesting the potential utility of mGluR5 positive allosteric modulators (PAMs) in the treatment of schizophrenia. Herein we describe the optimization of an mGluR5 PAM by replacement of a phenyl with aliphatic heterocycles and carbocycles as a strategy to reduce bioactivation in a biaryl acetylene chemotype. Replacement with a difluorocyclobutane followed by further optimization culminated in the identification of compound 32, a low fold shift PAM with reduced bioactivation potential. Compound 32 demonstrated favorable brain uptake and robust efficacy in mouse novel object recognition (NOR) at low doses.

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Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Awesome Chemistry Experiments For 15833-61-1

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 15833-61-1 is helpful to your research. Related Products of 15833-61-1

Related Products of 15833-61-1, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 15833-61-1, molcular formula is C5H10O2, introducing its new discovery.

ISOINDOLONE DERIVATIVES

Provided are compounds of formula (I), wherein A, Y, J, R1, R2, and R3 have any of the values defined therefor in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, diabetes, obesity, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).

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Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Discovery of (Tetrahydrofuran-3-yl)methanol

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 15833-61-1

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NEW INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS

The present invention relates to compounds of general for-mula I, wherein the groups R1, R2 and m are defined as in claim 1, which have valuable pharmacological properties, in particu-lar bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of dis-eases which can be influenced by this receptor, such as meta-bolic diseases, in particular diabetes type 2

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Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Brief introduction of (Tetrahydrofuran-3-yl)methanol

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Pyrolysis of alpha-cellulose using a multimode microwave oven

alpha-Cellulose was pyrolyzed using a multimode microwave oven, different microwave absorbers and experimental set ups. The microwave absorber showed a strong influence: carbon gave a large gasification of cellulose (yield of gas up to 53.8%) while Al2O3 gave a high yield of bio-char (64.1%) and a low gas production (3.0%). Bio-oil was obtained with the highest yield (37.6%) using iron as microwave absorber and a condenser between the oven and the collecting system. Dark brown bio-oils having low density and viscosity due to the presence of large amount of furanosidic compounds were collected. Bio-oils were characterized through GC?MS, FT-IR, NMR, The GC?MS analysis was employed to evaluate the composition of bio-oils using calculated retention factors. A high concentration of levoglucosan (133.9 mg/mL) together with acetic acid, acetic anhydride, 1-hydroxy-2-propanone, formic acid and furfural were obtained using graphite as microwave absorber. A mechanisms was proposed to rationalize the formation of aromatic compounds present in bio-oils. Water contents in bio-oils were affected by all parameters of the process, mainly by the microwave absorber. The use of silica has proved to be a promising way to obtain bio-oil with low water content (13%), while pyrolysis in the presence of carbon gave a large amount of water (46%).

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Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Brief introduction of (Tetrahydrofuran-3-yl)methanol

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HIGH CONCENTRATION DINOTEFURAN FORMULATIONS CONTAINING METHOPRENE

A topical insecticide is provided which can be safe to use and avoids many common deleterious side effects of conventional topical insecticides. In one preferred embodiment of the invention, the active ingredient of the insecticide formulation is an amine derivative, having a nitro-methylene group, a nitroamino group or a cyanoamino group, which can be formulated to have low toxicity and excellent insecticidal activity. One particularly suitable insecticide is 1{(tetrahydro-3-furanyl)methyl}-2-nitro-3-methylguanidine (dinotefuran), an aldulticide that will kill adult fleas combined with methoprene.

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Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Extracurricular laboratory:new discovery of 15833-61-1

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Direct mono-phosphorylation of 1,3-diols. A synthesis of FTY720-phosphate

A novel method for selective and direct phosphorylation of various 1,3-diols using silver(I) oxide, tetrabenzyl pyrophosphate (TBPP), and tetrahexylammonium iodide affording mono-phosphates was developed. We applied the present method to the synthesis of FTY720-phosphate.

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Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

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Through the Prins reaction to synthesize 3 – tetrahydrofuran methanol new process (by machine translation)

The invention discloses through Prins reaction to synthesize 3 – tetrahydrofuran-methanol of the new process, solved in the prior art in a manufacturing process, the raw materials are not only expensive, raising the production cost, but also the production process would release a large amount of heat and flammable and explosive gas hydrogen, will be brought to the production the security risk. The invention comprises (1) in the organic solvent, 2, 5 – dihydrofuran catalyst under the action of the A poly formaldehyde and hydrogen chloride reaction, to obtain the methyl – 2, 5 – dihydrofuran; (2) methyl 2, 5 – dihydrofuran in the sodium hydroxide solution is hydrolyzed to hydroxymethyl – 2, 5 – dihydrofuran, distilled to obtain crude; (3) crude hydroxy methyl – 2, 5 – dihydrofuran B under the action of the catalyst by the hydrogen reduction to obtain 3 – tetrahydrofuran methanol, filtering, rectifying the filtrate to obtain the pure product. The invention has the low cost of raw materials, little three-waste discharge, simple process and the like. (by machine translation)

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Furanyl insecticide

The present invention relates to novel (tetrahydro-3-furanyl)methylamino derivatives of the following formula (1): STR1 wherein the variables are defined in the specification, which are useful as insecticides.

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Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

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NEW PHENYLAZETIDINECARBOXYLATE OR -CARBOXAMIDE COMPOUNDS

The invention relates to compounds of formula (I). where R, R1, R2, n, A and Cy have the meanings indicated in the description. The compounds of formula (I) are Nurr-1 modulators.

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Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem