In 2022,Guillon, Jean; Savrimoutou, Solene; Albenque-Rubio, Sandra; Pinaud, Noel; Moreau, Stephane; Desplat, Vanessa published an article in Molbank. The title of the article was 《Synthesis, Crystal Structure and Anti-Leukemic Activity of 1,3-Dihydro-1-{1-[4-(4-phenylpyrrolo[1,2-a]quinoxalin-3-yl)benzyl]piperidin-4-yl}-2H-benzimidazol-2-one》.Application of 696-59-3 The author mentioned the following in the article:
Substituted pyrrolo[1,2-a]quinoxaline compound I was synthesized through a multi-step pathway starting from com. available 2-nitroaniline. A structure characterization of compound I was achieved by using FT-IR, 1H-NMR, 13C-NMR, X-Ray and HRMS spectral anal. This new compound I showed an interesting cytotoxic potential against several human leukemia cell lines (HL60, K562 and U937 cells).2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Application of 696-59-3) was used in this study.
2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Application of 696-59-3
Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem