Lin, Shaoying’s team published research in ChemCatChem in 9 | CAS: 19444-84-9

ChemCatChem published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Related Products of tetrahydrofurans.

Lin, Shaoying published the artcileEfficient Production of Biomass-Derived C4 Chiral Synthons in Aqueous Solution, Related Products of tetrahydrofurans, the publication is ChemCatChem (2017), 9(22), 4179-4184, database is CAplus.

Carbohydrates are expected to replace petroleum and to become the base of industrial chem. Chirality is one particular area in which carbohydrates have a special potential advantage over petroleum resources. Herein, we report a catalytic approach for the direct production of D-tetroses [i.e., D-(-)-erythrose and D-(+)-erythrulose] from D-hexoses through a fast retro-aldol process at 190° that achieves a yield of 46 % and completely retains the chiral centers in the final chiral synthon. The D-tetrose products were further converted into their derivatives, thereby accomplishing transfer of chirality from natural chiral hexoses to high-value-added chiral chems. Our results also suggest that the product distribution for the conversion of D-hexoses was determined by their isomerization and epimerization trends that competed with their corresponding retro-aldol condensation processes.

ChemCatChem published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Related Products of tetrahydrofurans.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Beijer, Barbro’s team published research in Nucleosides & Nucleotides in 13 | CAS: 87865-78-9

Nucleosides & Nucleotides published new progress about 87865-78-9. 87865-78-9 belongs to tetrahydrofurans, auxiliary class Nucleosides and Nucleotides,Nucleoside Analogues, name is N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, and the molecular formula is C26H45N5O7Si2, Category: tetrahydrofurans.

Beijer, Barbro published the artcileSimplified and cost effective syntheses of fully protected phosphoramidite monomers suitable for the assembly of oligo(2′-O-allylribonucleotides), Category: tetrahydrofurans, the publication is Nucleosides & Nucleotides (1994), 13(9), 1905-27, database is CAplus.

Simplified, high yielding syntheses of suitably protected 2′-O-allylribonucleoside-3′-O-phosphoramidites starting from standard ribonucleosides have been elucidated. Specific 2′-O-allylation is readily achieved using amidine protection of the exocyclic amino groups of adenosine and cytidine and in the case of guanosine the allylation is carried out on an easily prepared intermediate bearing transient protection of the lactam function.

Nucleosides & Nucleotides published new progress about 87865-78-9. 87865-78-9 belongs to tetrahydrofurans, auxiliary class Nucleosides and Nucleotides,Nucleoside Analogues, name is N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, and the molecular formula is C26H45N5O7Si2, Category: tetrahydrofurans.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Karpeisky, Alexander’s team published research in Nucleosides & Nucleotides in 16 | CAS: 87865-78-9

Nucleosides & Nucleotides published new progress about 87865-78-9. 87865-78-9 belongs to tetrahydrofurans, auxiliary class Nucleosides and Nucleotides,Nucleoside Analogues, name is N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, and the molecular formula is C26H45N5O7Si2, Synthetic Route of 87865-78-9.

Karpeisky, Alexander published the artcile2′-O-Methylthiomethyl modifications in hammerhead ribozymes, Synthetic Route of 87865-78-9, the publication is Nucleosides & Nucleotides (1997), 16(7-9), 955-958, database is CAplus.

The synthesis of all four phosphoramidites of 2′-O-methylthiomethyl ribonucleosides and their incorporation into hammerhead ribozymes and influence on nuclease stability and catalytic activity is described.

Nucleosides & Nucleotides published new progress about 87865-78-9. 87865-78-9 belongs to tetrahydrofurans, auxiliary class Nucleosides and Nucleotides,Nucleoside Analogues, name is N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, and the molecular formula is C26H45N5O7Si2, Synthetic Route of 87865-78-9.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Liang, Jian-lan’s team published research in Guoshu Xuebao in 31 | CAS: 19444-84-9

Guoshu Xuebao published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Category: tetrahydrofurans.

Liang, Jian-lan published the artcileChanges of aroma components in ‘Yanlong’ chestnut during storage, Category: tetrahydrofurans, the publication is Guoshu Xuebao (2014), 31(3), 410-414, database is CAplus.

This article was to study the changes of aroma components in ‘Yanlong’ chestnut during storage. The aroma components in chestnut stored 30 days, 90 days and 150 days, resp., were collected using solvent extraction, and analyzed by gas chromatograph-mass spectrophotometer (GC-MS). Totally 27 compounds were identified. Esters, ketones, aldehydes and alcs. were the major constituents. The aroma components accumulated differently during the storage. There were 17 components identified after storage for 30 days, 22 after 90 days and 22 after 150 days. During storage, the contents of esters and alkenes increased, and the contents of ketones and acids raised within 90 days and then kept stable, while the contents of alcs. showed highest after stored for 30 days and decreased until 90 days, then changed a little. Butyrolactone, 2-hydroxy-gamma-butyrolactone, 2,5-dimethyl-4-hy-droxy-3 (2H)-furanone, 4H-pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl-, furfural and 5-(hydroxymethyl)-2-Furancarboxaldehyde might be the characteristic aroma constituents of ‘Yanlong’ chestnut. Under the certain storage condition, the best time for tasting chestnut food was within 90 days after storage.

Guoshu Xuebao published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Category: tetrahydrofurans.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Bharali, Pankaj’s team published research in Current Science in 113 | CAS: 19444-84-9

Current Science published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Quality Control of 19444-84-9.

Bharali, Pankaj published the artcilePhytochemical and biochemical study of four legume plants with detergent and anti-lice properties from the Eastern Himalayan region of India, Quality Control of 19444-84-9, the publication is Current Science (2017), 113(7), 1434-1439, database is CAplus.

This study is aimed at the qual. and quant. investigation of the phytochem. content, macroand micronutrients, proximate anal. and determination of antioxidant activities of four plants belonging to the family Leguminosae namely Acacia pennata, Albizia lucidior, Albizia chinensis and Gymnocladus assamicus widely used by the Adi tribe of Arunachal Pradesh for their surfactant and insect-repellent properties. The methanol extract of the seed pod of G. assamicus, the most popular soap-plant among the Adi people, showed maximum 1,1-diphenyl-2-picrylhydrazyl scavenging activity with EC50 of 13.50 μg/mL and presence of hitherto reported insecticidal metabolites like 2-hydroxy-gamma-butyrolactone and heptadecene-(8)-carbonic acid.

Current Science published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Quality Control of 19444-84-9.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Sander, Kerstin’s team published research in Journal of Medicinal Chemistry in 58 | CAS: 19444-84-9

Journal of Medicinal Chemistry published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Recommanded Product: 3-Hydroxydihydrofuran-2(3H)-one.

Sander, Kerstin published the artcileDevelopment of Fluorine-18 Labeled Metabolically Activated Tracers for Imaging of Drug Efflux Transporters with Positron Emission Tomography, Recommanded Product: 3-Hydroxydihydrofuran-2(3H)-one, the publication is Journal of Medicinal Chemistry (2015), 58(15), 6058-6080, database is CAplus and MEDLINE.

Increased activity of efflux transporters, e.g., P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP), at the blood-brain barrier is a pathol. hallmark of many neurol. diseases, and the resulting multiple drug resistance represents a major clin. challenge. Noninvasive imaging of transporter activity can help to clarify the underlying mechanisms of drug resistance and facilitate diagnosis, patient stratification, and treatment monitoring. We have developed a metabolically activated radiotracer for functional imaging of P-gp/BCRP activity with positron emission tomog. (PET). In preclin. studies, the tracer showed excellent initial brain uptake and clean conversion to the desired metabolite, although at a sluggish rate. Blocking with P-gp/BCRP modulators led to increased levels of brain radioactivity; however, dynamic PET did not show differential clearance rates between treatment and control groups. Our results provide proof-of-concept for development of prodrug tracers for imaging of P-gp/BCRP function in vivo but also highlight some challenges associated with this strategy.

Journal of Medicinal Chemistry published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Recommanded Product: 3-Hydroxydihydrofuran-2(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Hua, Geng’s team published research in Journal of Polymer Science, Part A: Polymer Chemistry in 54 | CAS: 19444-84-9

Journal of Polymer Science, Part A: Polymer Chemistry published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Recommanded Product: 3-Hydroxydihydrofuran-2(3H)-one.

Hua, Geng published the artcileOne-pot inimer promoted ROCP synthesis of branched copolyesters using α-hydroxy-γ-butyrolactone as the branching reagent, Recommanded Product: 3-Hydroxydihydrofuran-2(3H)-one, the publication is Journal of Polymer Science, Part A: Polymer Chemistry (2016), 54(13), 1908-1918, database is CAplus and MEDLINE.

An array of branched poly(ε-caprolactone)s was successfully synthesized using an one-pot inimer promoted ring-opening multibranching copolymerization (ROCP) reaction. The biorenewable, com. available yet unexploited comonomer and initiator 2-hydroxy-γ-butyrolactone was chosen as the inimer to extend the use of 5-membered lactones to branched structures and simultaneously avoiding the typical tedious work involved in the inimer preparation Reactions were carried out both in bulk and in solution using stannous octoate (Sn(Oct)2) as the catalyst. Polymerizations with inimer equivalent varying from 0.01 to 0.2 were conducted which resulted in polymers with a degree of branching ranging from 0.049 to 0.124. Detailed ROCP kinetics of different inimer systems were compared to illustrate the branch formation mechanism. The resulting polymer structures were confirmed by 1H, 13C, and 1H-13C HSQC NMR and SEC (RI detector and triple detectors). The thermal properties of polymers with different degree of branching were investigated by DSC, confirming the branch formation. Through this work, we have extended the current use of the non-homopolymerizable γ-butyrolactone to the branched polymers and thoroughly examined its behaviors in ROCP. © 2016 Wiley Periodicals, Inc.J. Polym. Sci., Part A: Polym.Chem. 2016.

Journal of Polymer Science, Part A: Polymer Chemistry published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Recommanded Product: 3-Hydroxydihydrofuran-2(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Rayne, Sierra’s team published research in Flavour and Fragrance Journal in 31 | CAS: 57124-87-5

Flavour and Fragrance Journal published new progress about 57124-87-5. 57124-87-5 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Thiol, name is 2-Methyl-3-tetrahydrofuranthiol, and the molecular formula is C5H10OS, Synthetic Route of 57124-87-5.

Rayne, Sierra published the artcilepH dependent partitioning behaviour of food and beverage aroma compounds between air-aqueous and organic-aqueous matrices, Synthetic Route of 57124-87-5, the publication is Flavour and Fragrance Journal (2016), 31(3), 228-234, database is CAplus.

Aroma compounds in the Flavornet database were screened for ionizable functional groups such as carboxylic acids, aliphatic and aromatic amines, phenols, alcs. and thiols. Of the 738 aroma compounds listed in this database, 101 mols. have ionizable moieties with estimated monomeric aqueous pKa values ranging between 1.75 and 10.97. pH dependent effective air/water partitioning coefficients (Kaw,eff) and n-octanol/water partitioning coefficients (Dow) were estimated for all ionizable aroma compounds over the pH range from 0 to 14. The ionizable aroma compounds display a broad range of Kaw,eff (1.8 × 10-23 to 6.1 atm M-1) and log Dow (-6.2 to +7.2 units) values. For many aroma compounds, pH dependent ionization will have a significant effect on Kaw,eff and Dow, leading to variations in these physico-chem. properties by up to 11 orders of magnitude over the composite pH range of common foods and beverages. Changes in food and beverage pH affect not only the relative contributions of neutral vs. charged forms of ionizable aroma compounds (which directly affects analyte volatility and olfactory reception), but also partitioning between freely dissolved and sorbed forms of the analyte in solution (which indirectly affects analyte volatility). Copyright © 2015 John Wiley & Sons, Ltd.

Flavour and Fragrance Journal published new progress about 57124-87-5. 57124-87-5 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Thiol, name is 2-Methyl-3-tetrahydrofuranthiol, and the molecular formula is C5H10OS, Synthetic Route of 57124-87-5.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Semenyuk, Andrey’s team published research in Journal of the American Chemical Society in 128 | CAS: 87865-78-9

Journal of the American Chemical Society published new progress about 87865-78-9. 87865-78-9 belongs to tetrahydrofurans, auxiliary class Nucleosides and Nucleotides,Nucleoside Analogues, name is N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, and the molecular formula is C10H9IO4, HPLC of Formula: 87865-78-9.

Semenyuk, Andrey published the artcileSynthesis of RNA Using 2′-O-DTM Protection, HPLC of Formula: 87865-78-9, the publication is Journal of the American Chemical Society (2006), 128(38), 12356-12357, database is CAplus and MEDLINE.

Tert-butyldithiomethyl (DTM), a novel hydroxy protecting group, cleavable under reductive conditions, was developed and applied for the protection of 2′-OH during solid-phase RNA synthesis. This function is compatible with all standard protecting groups used in oligonucleotide synthesis, and allows for fast and high-yield synthesis of RNA. Oligonucleotides containing the 2′-O-DTM groups can be easily deprotected under the mildest possible aqueous and homogeneous conditions. The preserved 5′-O-DMTr function can be used for high-throughput cartridge RNA purification

Journal of the American Chemical Society published new progress about 87865-78-9. 87865-78-9 belongs to tetrahydrofurans, auxiliary class Nucleosides and Nucleotides,Nucleoside Analogues, name is N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, and the molecular formula is C10H9IO4, HPLC of Formula: 87865-78-9.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Makibar, Jon’s team published research in Fuel Processing Technology in 137 | CAS: 19444-84-9

Fuel Processing Technology published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Product Details of C4H6O3.

Makibar, Jon published the artcilePerformance of a conical spouted bed pilot plant for bio-oil production by poplar flash pyrolysis, Product Details of C4H6O3, the publication is Fuel Processing Technology (2015), 283-289, database is CAplus.

Poplar (Populus nigra) flash pyrolysis has been performed at the IK4-Ikerlan 25 kg h 1 pilot plant equipped with a conical spouted bed reactor. Gas, bio-oil and char yields and properties have been studied in the 425-525 °C range. This reactor has been proven to be especially suitable for this process as high bio-oil yields have been obtained, with the maximum being 69 weight% at 455 °C. The bio-oil has been collected in two fractions: the lighter one, which accounts for 85 weight% of the bio-oil, has a high water content and is composed mainly of acids and ketones, whereas the heavier fraction has a lower water content and is rich in phenols. These fractions are miscible, obtaining a bio-oil with a water content lower than 25 weight% and a higher heating value in the 16-18 MJ kg 1 range.

Fuel Processing Technology published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Product Details of C4H6O3.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem