Dellinger, Douglas J. published the artcileStreamlined Process for the Chemical Synthesis of RNA Using 2′-O-Thionocarbamate-Protected Nucleoside Phosphoramidites in the Solid Phase, Product Details of C26H45N5O7Si2, the publication is Journal of the American Chemical Society (2011), 133(30), 11540-11556, database is CAplus and MEDLINE.
An improved method for the chem. synthesis of RNA was developed utilizing a streamlined method for the preparation of phosphoramidite monomers and a single-step deprotection of the resulting oligoribonucleotide product using 1,2-diamines under anhydrous conditions. The process is compatible with most standard hetero-base protection and employs a 2′-O-(1,1-dioxo-1λ6-thio-morpholine-4-carbo-thioate) as a unique 2′-hydroxyl protective group. Using this approach, it was demonstrated that the chem. synthesis of RNA can be as simple and robust as the chem. synthesis of DNA.
Journal of the American Chemical Society published new progress about 87865-78-9. 87865-78-9 belongs to tetrahydrofurans, auxiliary class Nucleosides and Nucleotides,Nucleoside Analogues, name is N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide, and the molecular formula is C26H45N5O7Si2, Product Details of C26H45N5O7Si2.
Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem