Ali, Khursheed published the artcileAloe vera extract functionalized zinc oxide nanoparticles as nanoantibiotics against multi-drug resistant clinical bacterial isolates, Recommanded Product: 3-Hydroxydihydrofuran-2(3H)-one, the publication is Journal of Colloid and Interface Science (2016), 145-156, database is CAplus and MEDLINE.
ZnO nanoparticles (ZnONPs) were synthesized through a simple and efficient biogenic synthesis approach, exploiting the reducing and capping potential of Aloe barbadensis Miller (A. vera) leaf extract (ALE). ALE-capped ZnO nanoparticles (ALE-ZnONPs) were characterized using UV-Vis spectroscopy, x-ray diffraction (x-ray diffraction), Fourier transform IR (FTIR) spectroscopy, SEM, energy dispersive x-ray spectroscopy (EDX), and TEM analyses. X-ray diffraction anal. provided the average size of ZnONPs as 15 nm. FTIR spectral anal. suggested the role of phenolic compounds, terpenoids and proteins present in ALE, in nucleation and stability of ZnONPs. Flow cytometry and at. absorption spectrophotometry (AAS) data analyses revealed the surface binding and internalization of ZnONPs in Gram +ve (Staphylococcus aureus) and Gram -ve (Escherichia coli) cells, resp. Significant antibacterial activity of ALE-ZnONPs was observed against extended spectrum beta lactamases (ESBL) pos. E. coli, Pseudomonas aeruginosa, and methicillin resistant S. aureus (MRSA) clin. isolates exhibiting the MIC and MBC values of 2200, 2400 μg/mL and 2300, 2700 μg/mL, resp. Substantial inhibitory effects of ALE-ZnONPs on bacterial growth kinetics, exopolysaccharides and biofilm formation, unequivocally suggested the antibiotic and antibiofilm potential. Overall, the results elucidated a rapid, environmentally benign, cost-effective, and convenient method for ALE-ZnONPs synthesis, for possible applications as nanoantibiotics or drug carriers.
Journal of Colloid and Interface Science published new progress about 19444-84-9. 19444-84-9 belongs to tetrahydrofurans, auxiliary class Tetrahydrofuran,Ester,Alcohol, name is 3-Hydroxydihydrofuran-2(3H)-one, and the molecular formula is C4H6O3, Recommanded Product: 3-Hydroxydihydrofuran-2(3H)-one.
Referemce:
https://en.wikipedia.org/wiki/Tetrahydrofuran,
Tetrahydrofuran | (CH2)3CH2O – PubChem