Synthetic Route of C6H12O3In 2019 ,《Synthesis of N-substituted pyrrole derivatives via indium-assisted one-pot reduction/N-annulation sequence reaction》 appeared in Heterocycles. The author of the article were Kim, Eungyung; Jeong, Mingyeong; Lee, Hyejeong; Kim, Byeong Hyo. The article conveys some information:
A synthesis strategy toward diverse pyrrole derivatives I (R = n-pentyl, cyclohexyl, 2-chlorophenyl, quinolin-5-yl, etc.) via an indium-mediated one-pot reductive N-annulation reaction has been developed. This protocol provides easy access to versatile N-substituted pyrroles I in the presence of an indium/AcOH co-activation promotor, with excellent yields. The experimental process involved the reaction of 2,5-Dimethoxytetrahydrofuran(cas: 696-59-3Synthetic Route of C6H12O3)
2,5-Dimethoxytetrahydrofuran(cas: 696-59-3) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Synthetic Route of C6H12O3
Referemce:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem