4100-80-5, Name is 3-Methyldihydrofuran-2,5-dione, belongs to tetrahydrofurans compound, is a common compound. Application In Synthesis of 3-Methyldihydrofuran-2,5-dioneIn an article, once mentioned the new application about 4100-80-5.
Ketosantalic Acid, a New Sesquiterpenic Acid from Indian Sandalwood Oil
Indian sandalwood oil contains over one hundred constituents including about fifteen acids, some occuring only in traces.One of these is a new acid (11-keto-dihydro-alpha-santalic acid, 8), isolated as its methyl ester (9).Its structure has been determined on the basis of spectral and chemical evidences, including its conversion into the gamma-lactone (10) and the nitrogen-containing compound (12), formed via reduction with sodium borohydride and Wolff-Kishner reaction respectively.Products obtained by Beckmann rearrangement of the oxime (34) and Wagner-Meerwein/Nametkin rearrangement of 9 also provide supporting evidences. 9 is resistant to Baeyer-Villiger oxidation.Certain synthetic approaches yield bi-?-tricyclyl (30), teresantalol (26) and an unsaturated alcohol (29).Oxidation of alpha-santalyl acetate (37) with t-butyl chromate, instead of yielding the desired 11-keto-alpha-santalyl acetate (38), gives 12-acetoxy-13-keto-nor-alpha-santalane (40), formation of which has been rationalised.
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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem