Electric Literature of 117752-82-6, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.117752-82-6, Name is (S)-3-Amino-gamma-butyrolactone hydrochloride, molecular formula is C4H8ClNO2. In a Article£¬once mentioned of 117752-82-6
Convenient synthesis of 3-(S)-amino-gamma-butyrolactone
An efficient two step conversion of N-t-Boc-L-aspartic acid beta-benzyl ester to enantiopure 3-(S)-amino-gamma-butyrolactone is described. In this route, chemoselective reduction of the alpha-carboxylic group in the starting material via a mixed anhydride with NaBH4 afforded the corresponding alcohol in 95% yield without any loss of the optical purity. Subsequent acidic hydrolysis of the N-protected beta-amino alcohol not only deprotected the amino group, but also produced the desired gamma-lactone in 98% yield with complete retention of the optical activity.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 117752-82-6
Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem